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differentiation therapy

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differentiation therapy,
a cancer therapy technique in which the malignant cell is regarded as having escaped the normal controls of cell growth and differentiation. The cancer cell is regarded as pathologically arrested at an early stage of differentiation, retaining the ability to proliferate. It is treated with agents that remove this block and allow the cells to differentiate along more normal lines until they eventually lose their ability to divide and replicate.

differentiation therapy
Oncology A strategy used to treat malignancies with a block in the normal cell differentiation; the intent with DT is to drive malignant cells into a mature nonproliferating state of remission


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Conclusion Thus the dramatic finding that ATRA therapy was successful in APL was the first example of differentiation therapy in the treatment of advanced cancer.
SWCRF hosts international conferences that bring together differentiation therapy investigators in a major forum to share their findings with the scientific community.
About SWCRF Now in its 32nd year, the Samuel Waxman Cancer Research Foundation (SWCRF) "Institute Without Walls" is a unique non-profit international organization dedicated to supporting focused concept-driven research to develop targeted cancer cell-specific therapies, such as differentiation therapy.
 
 
 
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