Printer Friendly
Dictionary, Encyclopedia and Thesaurus - The Free Dictionary
3,590,294,284 visitors served.
forum Join the Word of the Day Mailing List For webmasters
?
Dictionary/
thesaurus
Medical
dictionary
Legal
dictionary
Financial
dictionary
Acronyms
 
Idioms
Encyclopedia
Wikipedia
encyclopedia
?

dideoxyinosine

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia 0.03 sec.
dideoxyinosine /di·de·oxy·in·o·sine/ (-in´o-sēn) didanosine.
di·de·ox·y·in·o·sine (dd-ks-n-sn, -sn, -n-)
n.
ddI.

dideoxyinosine (ddI)
[dī′dē·oksē·in′ōsēn]
an antiretroviral drug used in the treatment of human immunodeficiency virus infections. ddI inhibits the enzyme reverse transcriptase, thereby restricting viral replication activity. Inside the body, ddI is converted to dideoxyadenosine, which becomes incorporated into the deoxyribonucleic acid chain, interrupting its normal sequence and making viral replication impossible. Also called didanosine.

didanosine [di-dan´o-sēn]
a nucleoside analogueantiretroviral agent used for the treatment of advanced human immunodeficiency virus infection and acquired immunodeficiency syndrome; administered orally.

dideoxycytidine
(dī´dēok´sēsī´tidēn´),
n See Zalcitabine.
dideoxyinosine
(dī´dēok´sēin´-sēn´),
n See didanosine.


How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content.
?Page tools
Printer friendly
Cite / link
Feedback
Add definition
Mentioned in?  References in periodicals archive?   Medical browser?   Full browser?
 
Mitsuya's research led to the discovery of azidothymidine (AZT), dideoxyinosine (ddI) and dideoxycytidine (ddC), drugs with formidable potency against HIV.
Accelerated Approval * Didanosine (ddI, Dideoxyinosine, Videx), Bristol Myers-Squibb Approved October 9, 1991 for treatment of adult and pediatric patients with advanced HIV who are intolerant to or deteriorating on AZT.
To deflect the toxic effects of anti-AIDS medications such as zidovudine (AZT) or dideoxyinosine (ddI), HIV mutates.
 
 
 
Medical Dictionary
?

Terms of Use | Privacy policy | Feedback | Copyright © 2012 Farlex, Inc.
Disclaimer
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.