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dideoxyinosine

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia 0.02 sec.
dideoxyinosine /di·de·oxy·in·o·sine/ (-in´o-sēn) didanosine.
di·de·ox·y·in·o·sine (dd-ks-n-sn, -sn, -n-)
n.
ddI.

dideoxyinosine (ddI)
[dī′dē·oksē·in′ōsēn]
an antiretroviral drug used in the treatment of human immunodeficiency virus infections. ddI inhibits the enzyme reverse transcriptase, thereby restricting viral replication activity. Inside the body, ddI is converted to dideoxyadenosine, which becomes incorporated into the deoxyribonucleic acid chain, interrupting its normal sequence and making viral replication impossible. Also called didanosine.

dideoxycytidine
(dī´dēok´sēsī´tidēn´),
n See Zalcitabine.
dideoxyinosine
(dī´dēok´sēin´-sēn´),
n See didanosine.


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Didanosine (ddI, Dideoxyinosine, Videx), Bristol Myers-Squibb
To deflect the toxic effects of anti-AIDS medications such as zidovudine (AZT) or dideoxyinosine (ddI), HIV mutates.
Patients who show signs of resistance to zidovudine can switch to another antiviral drug such as dideoxyinosine, he adds.
 
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