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dideoxycytidine

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dideoxycytidine /di·de·oxy·cy·ti·dine/ (-si´tĭ-dēn) a dideoxynucleoside in which the base is cytosine; it is an antiretroviral agent that acts by inhibiting reverse transcriptase and is used in treating acquired immunodeficiency syndrome.
di·de·ox·y·cy·ti·dine (dd-ks-st-dn)
n.
ddC.

dideoxycytidine
[dī′dē·ok′sēsī′tidēn]

dideoxycytidine [-si´tĭ-dēn]
an antiretroviral agent whose base is cytosine; it acts by inhibiting reverse transcriptase and is used in treating human immunodeficiency virus infection and aids.

dideoxycytidine
(dī´dēok´sēsī´tidēn´),
n See Zalcitabine.
dideoxyinosine
(dī´dēok´sēin´-sēn´),
n See didanosine.


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Mitsuya's research led to the discovery of azidothymidine (AZT), dideoxyinosine (ddI) and dideoxycytidine (ddC), drugs with formidable potency against HIV.
Zalcitabine (ddC, Dideoxycytidine, HIVID), Hoffmann-La Roche Approved June 19, 1992 for combination use with AZT for the treatment of selected patients with advanced HIV disease.
A panel of the Food and Drug Administration (FDA) advised approval of the anti-AIDS drug dideoxycytidine (DDC) for use in conjunction with AZT (141:303).
 
 
 
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