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dicumarol

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dicumarol /di·cu·ma·rol/ (di-koo´mah-rol) a coumarinanticoagulant, which acts by inhibiting the hepatic synthesis of vitamin K–dependent coagulation factors.
di·cu·ma·rol (d-km-rôl, -rl)
n.
An anticoagulant that inhibits the formation of prothrombin in the liver. Also called bishydroxycoumarin.
dicoumarol, dicumarol
a potent anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent clotting factors (prothrombin and factors VII, IX and X) in the liver; used in the prevention and treatment of thromboembolic disorders. Produced naturally by conversion of nontoxic coumarin in moldy sweet clover hay, lespepeza hay or sweet vernal hay. Eating the hay causes blood loss due to spontaneous hemorrhage. Formerly called bishydroxycoumarin. See also melilotus, anthoxanthum odoratum lespedeza.
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Dicumarol is a potent drug that prevents blood from coagulating to form clots.
NEEDLE-FREE INSULIN MAY COME FOR DIABETICS, RESEARCHERS SAY by Daily News (Los Angeles, CA)
8, containing 40 [micro]M dicumarol, and 50 [micro]L of a 20 [micro]M stock solution of ethoxyresorufin with 1.
Aryl hydrocarbon receptor-mediated activity of particulate organic ... by Washburn, Barbara Shayne / Environmental Health Perspectives
In another set of experiments, 10 [micro]m dicumarol, an inhibitor of cytosolic QR, was added to the reaction mixture to assure that the disappearance of the substrate was due to a cytosolic QR enzyme reaction.
Inhalation exposure of rats to asphalt fumes generated at paving ... by Castranova, Vince / Environmental Health Perspectives
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