diclofenac


Also found in: Dictionary, Thesaurus, Wikipedia.
Related to diclofenac: diclofenac sodium

diclofenac

 [di-klo´fen-ak]
a nonsteroidal anti-inflammatory drug used systemically as the potassium or sodium salt in the treatment of rheumatic and nonrheumatic inflammatory conditions, and as the potassium salt to relieve pain and dysmenorrhea; also applied topically to the conjunctiva as the sodium salt to reduce ocular inflammation or photophobia after certain kinds of surgery and to the skin to treat actinic keratoses.

diclofenac

/di·clo·fen·ac/ (di-klo´fen-ak) a nonsteroidal anti-inflammatory drug used as the potassium or sodium salt in the treatment of rheumatic and nonrheumatic inflammatory conditions, and as the potassium salt to relieve pain and dysmenorrhea; also applied topically to the conjunctiva as the sodium salt to reduce ocular inflammation or photophobia after certain kinds of surgery and to the skin to treat actinic keratoses.

diclofenac

(dī′klō-fĕn′ăk)
n.
A nonsteroidal anti-inflammatory drug, C14H11Cl2 NO2, used in the form of its potassium salt to treat pain.

diclofenac

[diklo′fenak]
a nonsteroidal antiinflammatory drug used systemically as the potassium or sodium salt in the treatment of rheumatic and nonrheumatic inflammatory conditions and as the potassium salt to relieve pain and dysmenorrhea. It is also applied topically to the conjunctiva as a sodium salt to reduce ocular inflammation or photophobia after certain kinds of surgery and to the skin to treat actinic keratoses.

diclofenac

A non-steroidal anti-inflammatory drug (NSAID) used in the treatment of RHEUMATOID ARTHRITIS and other painful conditions. Brand names are Dicloflex, Diclomax, Motifene, Volraman, Volsaid Retard and Voltarol.

antiinflammatory drug 

A drug which inhibits or suppresses most inflammatory responses of an allergic, bacterial, traumatic or anaphylactic origin, as well as being immunosuppressant. They include the corticosteroids (e.g. betamethasone, dexamethasone, fluorometholone, hydrocortisone acetate, loteprednol etabonate, prednisolone, rimexolone, triamcinolone). They are sometimes combined with an antibiotic drug (e.g. betamethasone combined with neomycin or sulfacetamide, dexamethasone combined with neomycin or polymyxin B). Corticosteroids have side effects, such as enhancing the activity of herpes simplex virus, fungal overgrowth, raising intraocular pressure or cataract formation.There are other antiinflammatory drugs that are non-steroidal (NSAID) and have little toxicity. They act mainly by blocking prostaglandin synthesis. These include diclofenac sodium, flurbiprofen sodium, indomethacin, ketorolac, nepafenac and oxyphenbutazone. See immunosuppressants; steroid.

diclofenac

(dīklō´fənak´),
n brand names: Cataflam, Voltaren;
drug class: nonsteroidal antiinflammatory;
action: inhibits prostaglandin synthesis;
uses: acute and chronic rheumatoid arthritis, osteoarthritis, ankylosing spondylitis.

diclofenac

a nonsteroidal anti-inflammatory agent, used topically in ophthalmic diseases.

Patient discussion about diclofenac

Q. HELP...has anyone taken Diclofenac? And did you have any side affects? My boyfriend has started this medication and it is messing with his stomach which we know is a side affect BUT we are wondering if it will get better as his body adjust to it or will it always be this way. THANKS FOR ANY HELP! He is taking for inflamation and back pain.

A. Dear brwnis65, I have been on Diclofenac Sodium 75mg EC 2 a day, for about 2 years now. I have a bad back and arthuritis. What works for me is taking it at night AFTER my evening meal. I also take Prilosec in the morning to help with my reflux problem. I have had no problems with the Diclofenac and my stomach. Make sure you drink a full glass of water when you swallow your pill. Good Luck. egglady1955

More discussions about diclofenac
References in periodicals archive ?
Four Class I studies (defined as well-designed, double-blind, randomized, placebo-controlled trials) evaluating diclofenac potassium were included in the AHS Assessment, and they showed that patients taking diclofenac potassium were more likely to be headache-free at two hours or had reduced two-hour headache intensity than those taking placebo.
Moreover, it appears that curcumin is able to improve the effect of subanalgesic doses of diclofenac in the formalin-induced orofacial pain in rats (Mittal et al.
Rinkita Gurav from the Bombay Natural History Society - a member of the international Save consortium - said that it was vital to "remove diclofenac from the market completely".
Interestingly, the curcumin group also had a greater reduction in overall inflammation (rheumatoid arthritis may have slightly improved) compared to the diclofenac group.
Groundnut oil-entrapped TSP-alginate beads containing diclofenac sodium were prepared by ionotropically emulsion-gelation technique.
In the other hand, diclofenac acetate is an effective and relatively harmless non-steroid medicine.
Patients on Traumeel gel averaged a 71% reduction; the diclofenac gel group had a median 69% reduction.
The first group consisted of patients receiving diclofenac sodium and an alpha-blocker, the second group of patients received diclofenac sodium and prednisolone, and the third group of patients received diclofenac sodium alone.
The use of diclofenac in animals has been reported to a sharp decline in the vulture population in the Indian subcontinent.
A notice posted on the FDA's Med-Watch site said that the manufacturers--Endo Pharmaceuticals and Novartis Consumer Health--had revised the "hepatic effects" section of the diclofenac topical gel label to include new warnings and precautions.
The five arms were: 1) Pennsaid plus oral placebo, 2) topical placebo containing a small amount of DMSO for blinding purposes (DMSO facilitates delivery of diclofenac to the knee) plus oral placebo, 3) topical vehicle-control (containing the same concentration of DMSO as in Pennsaid) plus oral placebo, 4) topical placebo plus oral diclofenac and 5) Pennsaid plus oral diclofenac.
Diclofenac Sodium Ophthalmic Solution is a non-steroidal anti-inflammatory agent used to treat cataract and refractive surgery patients.