dichlorphenamide

dichlorphenamide

 [di″klor-fen´ah-mīd]
a carbonic anhydrase inhibitor used in the treatment of glaucoma.

dichlorphenamide

/di·chlor·phen·a·mide/ (di″klor-fen´ah-mīd) a carbonic anhydrase inhibitor; used as an adjunct to reduce intraocular pressure in the treatment of glaucoma.

dichlorphenamide

[dī′klôrfen′əmīd]
a carbonic anhydrase inhibitor.
indications It is prescribed in the treatment of chronic open-angle glaucoma and before surgery for angle-closure glaucoma.
contraindications Liver and adrenocortical insufficiency, kidney failure, hyperchloremic acidosis, depressed sodium or potassium level, pulmonary obstruction, Addison's disease, known or suspected pregnancy, or known hypersensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse reactions are anorexia, GI disturbances, acidosis, ureteral calculus formation, and aplastic anemia.

dichlorphenamide

A DIURETIC drug with a short duration of action. It is also used in the treatment of GLAUCOMA. A brand name is Daranide.

carbonic anhydrase inhibitors 

Drugs which inhibit the carbonic anhydrase enzyme in the ciliary epithelium of the ciliary body. This enzyme is essential for the formation of aqueous humour; its reduction results in a decrease in intraocular pressure. Those in use are sulfonamide derivatives. They are administered systemically (e.g. acetazolamide) or topically in the treatment of glaucoma. Examples: acetazolamide, brinzolamide, dichlorphenamide, dorzolamide.

dichlorphenamide

a carbonic anhydrase inhibitor used to reduce intraocular pressure in glaucoma.
References in periodicals archive ?
After a series of companies bought and sold the right to the decades-old dichlorphenamide, the list price was hiked from $50 to $13,650 for 100 pills in 2015.
As recently as the early 2000s, patients could obtain 100 pills of dichlorphenamide at a list price of $50, the senators wrote.
2,4,6) Mechanism Drug Class Preparations of Action Reduction Adrenergic Brimonidine of Aqueous agonists Apraclonidine Inflow [beta]-blockers Non-selective Timolol Levobunolol Carteolol Selective [beta]-blockers Betaxolol Carbonic Systemic anhydrase Acetazolamide inhibitors Methazolamide Dichlorphenamide Topical Dorzolamide Brinzolamide Increase Cholinergics Pilocarpine in Aqueous Increase Carbachol Outflow trabecular outflow Prostaglandins Latanoprost (xalatan) and other lipid Travoprost (travatan) receptor agonists Increase Bimatoprost (lumigan) uveoscleral Unoprostone outflow Table 2: The Demographic Data of the Patients of POAG Selected for the Study Bimatoprost Timolol Maleate No.
Additionally, acetazolamide, dichlorphenamide, and carbonic anhydrase inhibitors are not generally recommended for the preventive treatment of migraines but maybe effective for the prevention of VM [82].
channel inhibitor Carbonic Acetazolamide Prototypical drug; not used for anhydrase treating hypertension or heart failure inhibitors Dichlorphenamide Not used for treating hypertension or heart failure Methazolamide Not used for treating hypertension or heart failure Table 5.
9) Dichlorphenamide was administered orally to 2 raptors with suspected glaucoma at the dose rate used in dogs and buphthalmos resolved in one case.
Use of dichlorphenamide in two cases of glaucoma in owls.
These include acetazolamide (Diamox), dichlorphenamide (Daranide) and methazolamide (Neptazane).
Miscellaneous medications: clofibrate, dichlorphenamide, fenfluramine, ketoconazole, methadone, methazolamide, norethindrone, thiabendazole
Trusopt should not be taken while patients are wearing soft contact lenses and is not recommended for those patients taking oral CAIs such as acetazolamide or dichlorphenamide.