diastolic heart failure


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diastolic heart failure

Cardiology Heart failure with preserved left ventricular systolic function–LV ejection fraction of ≥ 50%, no segmental wall motion abnormalities, and no evidence of significant coronary, valvular, infiltrative, pericardial, or pulmonary disease; although DHF is less severe than typical systolic HF in terms of pathophysiologic characteristics, both have severely reduced exercise capacity, neuroendocrine activation and impaired quality of life. See Heart failure. Cf Systolic heart failure.

diastolic heart failure

Heart failure in which systolic function is preserved-the left ventricular ejection fraction is normal. During diastole there is abnormal left ventricle relaxation with increased stiffness of the chamber. Doppler echocardiography is usually necessary to establish the diagnosis.
References in periodicals archive ?
Hypertension is the cause in the overwhelming majority of diastolic heart failure cases.
s) for the treatment of systolic and diastolic heart failure.
Elevation of plasma brain natriuretic peptide is a hallmark of diastolic heart failure independent of ventricular hypertrophy.
B-type natriuretic peptide strongly reflects diastolic wall stress in patients with chronic heart failure: comparison between systolic and diastolic heart failure.
a developer of novel therapeutic devices for Diastolic Heart Failure (DHF), announced today that it has raised $5.
Gaasch will lead a panel discussion titled, "Management Strategies for Patients With Diastolic Heart Failure.
Diastolic heart failure is particularly common among people with diabetes, and our intent is that at least one-half of the subjects enrolled in this study will have diabetes.
COMPASS-HF evaluated the use of a new, investigational device, the Chronicle(R) implantable hemodynamic monitor (IHM) that is designed to continuously track intracardiac pressure, body temperature, physical activity and heart rate in patients with systolic and diastolic heart failure (NYHA Class III and IV).
The second study, by researchers at Christ Advocate Hospital, Chicago, demonstrated the BioZ's stroke volume (SV) measurement as an important parameter to identify diastolic heart failure and monitor effectiveness of therapy.
The improved classification of CHF aids in the management and treatment, which can be considerably different for systolic versus diastolic heart failure.
We are also moving forward with our alagebrium program, which began enrollment last month in a Phase 2 study for diastolic heart failure in Haptoglobin 2-2 diabetic patients, which complements a second Phase 2 study in systolic heart failure, begun last November and almost half enrolled.