diabetic glomerulosclerosis

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Related to diabetic glomerulosclerosis: amyloidosis


diabetic glomerulosclerosis (intercapillary glomerulosclerosis) a degenerative complication of diabetes mellitus in which there is glomerular mesangial expansion with either diffuse lesions or nodular (Kimmelstiel-Wilson) lesions; symptoms include albuminuria, nephrotic edema, hypertension, renal insufficiency, and retinopathy. The type with nodular lesions is also called Kimmelstiel-Wilson syndrome.
focal segmental glomerulosclerosis focal sclerosing lesions of the renal glomeruli, with proteinuria, hematuria, hypertension, and the nephrotic syndrome; it may be idiopathic or secondary to another condition. Called also focal glomerular sclerosis.

di·a·bet·ic glo·mer·u·lo·scle·ro·sis

proteinuria and ultimately, renal failure occuring in long-standing diabetes, and characterized by rounded hyaline or laminated nodules in the periphery of the glomeruli with capillary basement membrane thickening, and increased mesangial matrix.Synonym(s): intercapillary glomerulosclerosis

di·a·bet·ic glo·mer·u·lo·scler·o·sis

(dī-ă-bet'ik glŏ-mer'yū-lō-skler-ō'sis)
Rounded hyaline or laminated nodules in the periphery of the glomeruli with capillary basement membrane thickening and increased mesangial matrix occurring in long-standing diabetes, proteinuria, and ultimately renal failure.
Synonym(s): intercapillary glomerulosclerosis.

diabetic glomerulosclerosis

A type of glomerulosclerosis seen in some cases of diabetes mellitus. Eosinophilic material is present in various parts of the glomerulus.
Synonym: intercapillary glomerulosclerosis
References in periodicals archive ?
A re-evaluation of diabetic glomerulosclerosis 50 years after the discovery of insulin.
15) This early description of the glomerular tip lesion was not restricted to FSGS, but rather a novel report of a curious glomerular abnormality seen independently in patients with proteinuria as well as being found in other heterogeneous renal abnormalities with associated proteinuria, including membranous glomerulopathy and diabetic glomerulosclerosis.