diabetic embryopathy

diabetic embryopathy

A complex of congenital anomalies that affect ± 10% of children born to diabetic mothers, which develops in the 5th-8th wk of gestation Clinical Sacral agenesis, holoprosencephaly, atrioventricular septal defects, tetralogy of Fallot, other cardiac, genitourinary, and GI defects. See Honeybee syndrome.
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The overall incidence of diabetic embryopathy is 6%-10%, which is five times higher than in nondiabetics.
Diabetic embryopathy accounts for about 40% of deaths of infants of diabetic mothers.