dextromethorphan


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dextromethorphan

 [dek″stro-meth´or-fan]
a synthetic morphine derivative used as an antitussive in the form of the hydrobromide salt.

dextromethorphan

/dex·tro·meth·or·phan/ (-meth-or´fan) a synthetic morphine derivative used as an antitussive; used in the form of the base or as the hydrobromide salt or sulfonated styrene-divinylbenzene (polistirex) copolymer.

dextromethorphan

(dĕk′strō-mə-thôr′făn)
n.
An antitussive drug, C18H25NO, that is used in its hydrobromide form and is less addictive than codeine.

dextromethorphan

DXM, poor man's Ecstasy Substance abuse A opiate in some cough syrups which, in megadoses required to get the desired mind-altering effect, has many of the effects of Ecstasy–eg euphoria, hallucinations Route Oral Pharmacologic effects ↓ Cough-center response; mimics codeine's effects without analgesia Uses Suppresses nonproductive cough Toxicity Respiratory depression, coma, death. See Ecstasy, Roboing.

dextromethorphan

An opioid drug, with little useful pain-killing action, used to control persistent and unproductive cough. The drug is on the WHO official list.

dextromethorphan

a synthetic morphine derivative used as an antitussive in the form of the hydrobromide salt.
References in periodicals archive ?
Dextromethorphan plus ultra low-dose quinidine reduces pseudobulbar affect.
The most noteworthy safety finding was an increased rate of falls among patients on dextromethorphan plus quinidine, a 9% rate, compared with a 4% rate in the controls, a signal for this adverse effect not previously seen in other studies of dextromethorphan plus quinidine.
A single dose of dextromethorphan, however, reduced the women's pain response to the testswith women with fibromyalgia benefiting as much as those without the condition.
5 [micro]M) and dextromethorphan (50-400 [micro]M) were used for inhibition kinetics studies.
Interpretation & conclusion: The results indicated that codeine, dextromethorphan and dextropropoxyphene were devoid of genotoxicity in mice.
While our findings and the absence of contemporary studies supporting the use of dextromethorphan continue to question its effectiveness for the treatment of cough associated with upper respiratory tract infections, we have now provided evidence supporting honey, which is generally regarded as safe for children older than one year, as an alternative," the authors conclude.
A recent study in children and adolescents between the ages of 2-18 compared dextromethorphan to honey and to no treatment for coughs associated with upper respiratory infections.
The antitussive dextromethorphan has been associated with abuse by school-aged children and adolescents due to the euphoric effects caused by high doses of the drug (Carr, 2006).
The company spokesman said most customers using cold and cough medicines containing dextromethorphan purchase small amounts, typically one item.
A teenage boy this past weekend overdosed on cold medication containing dextromethorphan, which he said he had purchased at a Giant Food Store in Camp Hill, Pa.
On the market since the 1960s, dextromethorphan is used in small doses for cough suppression.
Most cough syrups contain dextromethorphan, which the ACCP says is ineffective in stopping coughs, the most common reason people seek medical attention.