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dexmedetomidine/dex·med·e·to·mi·dine/ (-med-ĕ-to´mĭ-dēn) a selective α agonist, used as the hydrochloride salt as a sedative for patients in intensive care units.
an alpha2 adrenoceptor agonist sedative.
indications It is used to sedate mechanically ventilated and intubated patients in the intensive care unit.
contraindications Known hypersensitivity to this drug contraindicates its use.
adverse effects Life-threatening effects are atrial fibrillation and infarction. Other serious adverse effects include oliguria, hypertension, pulmonary edema, pleural effusion, hypoxia, leukocytosis, and anemia. Common side effects include nausea, bradycardia, and hypotension.