dexmedetomidine


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dexmedetomidine

 [deks″med-ĕ-to´mĭ-dēn]
a selective α2-adrenergic receptor agonist, used as the hydrochloride salt as a sedative for patients in intensive care units; administered intravenously.

dexmedetomidine

/dex·med·e·to·mi·dine/ (-med-ĕ-to´mĭ-dēn) a selective α agonist, used as the hydrochloride salt as a sedative for patients in intensive care units.

dexmedetomidine

an alpha2 adrenoceptor agonist sedative.
indications It is used to sedate mechanically ventilated and intubated patients in the intensive care unit.
contraindications Known hypersensitivity to this drug contraindicates its use.
adverse effects Life-threatening effects are atrial fibrillation and infarction. Other serious adverse effects include oliguria, hypertension, pulmonary edema, pleural effusion, hypoxia, leukocytosis, and anemia. Common side effects include nausea, bradycardia, and hypotension.

dexmedetomidine

Anesthesiology A selective α2-adrenoceptor agonist, which ↓ the dose of isoflurane required for anesthesia during abdominal hysterectomy. See Isoflurane.
References in periodicals archive ?
Electronic Auction: Supply of dexmedetomidine for the needs of the Federal Service for Health Care and Social Development of the Russian Federation Ministry of Health (Chelyabinsk) with a procurement participant who is a small business entity, a socially-oriented non-profit organization
The administration of dexmedetomidine may reduce the incidence of respiratory system complications.
Dexmedetomidine is a potent and highly selective a-2-adrenoceptor agonist with analgesic potency.
9,10,11,12] Dexmedetomidine is a new highly selective and potent alpha-2 adrenoceptor agonist offering sedation and anxiolysis, has analgesic qualities and reduce the stress response to surgery and intensive care procedure.
At present, clonidine and dexmedetomidine are the two alpha-2 agonist commonly used in clinical practice.
Dexmedetomidine use has been reported in cases with paroxysmal autonomic instability with dystonia and in tetanus.
In clinical practice we noticed that patients given dexmedetomidine were less agitated after surgery.
A frequent side effect of dexmedetomidine is bradycardia--slowing of the heart rate--which can be substantial and dangerous during general anesthesia," Dr.
Researchers have tested drugs like Meperidine, Dexmedetomidine, Tramadol, clonidine, Ketamine etc.
Dexmedetomidine is an intravenous drug used to sedate patients during surgery which can also cause hypertension or hypotension that may increase patient risk.
Recro Pharma, a revenue generating specialty pharmaceutical company, has announced positive efficacy results in the Phase II clinical trial for Dex-IN, a proprietary intranasal formulation of dexmedetomidine, it was reported yesterday.