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dexmedetomidine

   Also found in: Wikipedia 0.01 sec.
dexmedetomidine /dex·med·e·to·mi·dine/ (-med-ĕ-to´mĭ-dēn) a selective α agonist, used as the hydrochloride salt as a sedative for patients in intensive care units.
dexmedetomidine,
an alpha2 adrenoceptor agonist sedative.
indications It is used to sedate mechanically ventilated and intubated patients in the intensive care unit.
contraindications Known hypersensitivity to this drug contraindicates its use.
adverse effects Life-threatening effects are atrial fibrillation and infarction. Other serious adverse effects include oliguria, hypertension, pulmonary edema, pleural effusion, hypoxia, leukocytosis, and anemia. Common side effects include nausea, bradycardia, and hypotension.

dexmedetomidine [deks″med-ĕ-to´mĭ-dēn]
a selective α2-adrenergic receptor agonist, used as the hydrochloride salt as a sedative for patients in intensive care units; administered intravenously.

dexmedetomidine
Anesthesiology A selective α2-adrenoceptor agonist, which ↓ the dose of isoflurane required for anesthesia during abdominal hysterectomy. See Isoflurane.


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Dexmedetomidine (PreceDEX) has recently been approved as an agent of choice in office sedation.
Intravenous dexmedetomidine was administered in 52 patients (average age, 60 years; 30 men) and intravenous lorazepam in 51 patients (average age, 59 years; 23 men).
 
 
 
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