features of functional bladder outlet obstruction on electromyography, such as detrusor sphincter dyssynergia
Placebo controlled, randomised, double blind study of the effects of botulinum A toxin on detrusor sphincter dyssynergia
in multiple sclerosis patients.
Problems reported in some patients included detrusor sphincter dyssynergia (high urethral resistance), poor voiding responses, leg contractions, and pain.
Detrusor sphincter dyssynergia can occur in individuals following SCI.
Patients with poor bladder compliance, detrusor sphincter dyssynergia
or outlet obstruction can develop a functional obstruction due to raised intravesical pressures.
Joy and Johnston (2001) suggest that 90% of people with MS experience bladder dysfunction at some point; detrusor hyperreflexia, detrusor sphincter dyssynergia
, and detrusor areflexia are the three most common types.
Botox has also been studied in detrusor sphincter dyssynergia
(DSD), which causes urinary urgency, frequency, incontinence, difficulties emptying the bladder, and urinary infections in people with MS.
Nine patients were excluded (2 had meatotomy, 1 postoperative retention and fixation of supra-pubic catheter, 1 detrusor sphincter dyssynergia
, 3 re-do, 1 with urethral stricture and proximal diverticulum, 1 fistula).