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detrusor overactivity

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detrusor overactivity,
involuntary contractions of the detrusor urinae muscle from any cause. Also called detrusor hyperactivity, detrusor hyperreflexia.


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It appears, however, that detrusor contractility bladder capacity, and the ability to withhold voiding decline in both sexes; the maximal urethral closure pressure and length probably decline in women; detrusor overactivity increases in prevalence; and the post voiding residual (PVR) urine volume probably increases to 50 mL to 100 mL.
The study will determine the safety and effectiveness of an investigational medication in managing the symptoms of urinary incontinence caused by neurogenic detrusor overactivity in both men and women who have MS or a spinal cord injury (SCI) and have not been adequately managed with anticholinergic therapy.
 
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