desmopressin


Also found in: Dictionary, Wikipedia.

desmopressin

 [des″mo-pres´in]
a synthetic analogue of vasopressin, used as an antidiuretic in central diabetes insipidus and in primary nocturnal enuresis, and as an antihemorrhagic in hemophilia a and von willebrand's disease.

des·mo·pres·sin

(des'mō-pres'in),
An analogue of vasopressin (antidiuretic hormone, ADH) with powerful antidiuretic activity.

desmopressin

/des·mo·pres·sin/ (des″mo-pres´in) a synthetic analogue of vasopressin, used as the acetate salt as an antidiuretic in central diabetes insipidus and in primary nocturnal enuresis, and as an antihemorrhagic in hemophilia A and von Willebrand's disease.

des·mo·pres·sin

(des'mō-pres'in)
An analogue of vasopressin (antidiuretic hormone, ADH) possessing powerful antidiuretic activity.

desmopressin

A drug used in the treatment of DIABETES INSIPIDUS. Desmopressin, or DDAVP, is a long-acting analogue of the natural pituitary hormone vasopressin, which is deficient in this condition. The drug is given in a nasal spray or in the form of nose drops. The drug is on the WHO official list. Brand names are DDAVP, Desmospray and Desmotabs.

Desmopressin (DDAVP)

A drug used in the treatment of von Willebrand's disease.

desmopressin

a synthetic analog of 8-arginine vasopressin; the acetate (DDAVP) is used for antidiuretic replacement therapy in the management of central diabetes insipidus and for the temporary polyuria and polydipsia associated with trauma to or surgery in the pituitary region.
References in periodicals archive ?
At the meeting last month, the FDA Endocrinologic and Metabolic Drugs Advisory Committee voted 10-5, with 2 abstentions, that the benefits of this desmopressin formulation in clinical trials did not outweigh the risks for the proposed indication, the treatment of nocturia due to nocturnal polyuria in adults who wake up two or more times each night to void.
Due to the transient nature of the condition, desmopressin treatment should be given as needed in doses of 1-2 [micro]g administered subcutaneously, intravenously or intramuscularly or 10 [micro]g intranasally once the nasal packing is removed (6).
Hematologists and other specialists based in Europe, the US, and Australia cover the history of the bleeding disorder; the biosynthesis and organization, structure and function, and modulation of von Willebrand factor; animal models; bleeding history; classification; epidemiology; laboratory and molecular diagnosis; clinical, laboratory, and molecular markers of the three types; aspects related to children and women; the use of desmopressin and plasma-derived concentrates; prophylaxis; and gene therapy.
In the case of children and young people over seven years, for whom an alarm is inappropriate or ineffective, NICE recommends Desmopressin or its combined use with an alarm.
If rapid-onset or short-term improvement is required or the family cannot use an alarm at this moment in time, they may want to consider desmopressin medication.
Farmakolojik tedavi yaklasimlarinda desmopressin ve antikolinerjiklerin yani sira antidepresanlar da alternatif olarak kullanilmaktadir.
On administration of 4 [micro]g desmopressin, urinary output fell to around 100 ml/hour and serum sodium returned to 147 mmol/l, in keeping with a diagnosis of central diabetes insipidus.
Desmopressin acetate, a synthetic analogue of the natural pituitary hormone ADH, is used in the management of central diabetes insipidus.
Antihemophilic Factor/von Willebrand Factor Complex (Human), Alphanate(R), is also indicated for surgical and/or invasive procedures in patients with von Willebrand Disease (VWD), except Type 3 patients undergoing major surgery, in whom desmopressin (DDAVP(R)) is either ineffective or contraindicated.
Intravenous desmopressin in an amount of 2 000 ampoules.