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desmoplasia

   Also found in: Encyclopedia, Wikipedia 0.01 sec.
desmoplasia /des·mo·pla·sia/ (dez″mo-pla´zhah) the formation and development of fibrous tissue.desmoplas´tic
des·mo·pla·sia (dzm-plzh)
n.
The formation and proliferation of fibroblasts and fibrous connective tissue, especially in tumors.

desmoplasia [dez″mo-pla´zhah]
the formation and development of fibrous tissue. adj., adj desmoplas´tic.

desmoplasia
the formation and development of fibrous tissue, usually indicating that caused by neoplastic processes.

Patient discussion about desmoplasia.

Q. Do women with cystic fibrosis have difficult pregnancy? My wife has cystic fibrosis, and after 3 year of marriage we decided we want a baby. I know that men with cystic fibrosis are usually infertile and can’t have children- is that the case also for women with cystic fibrosis? Is the pregnancy in women with cystic fibrosis more problematic? Is it dangerous?

A. Before you attempt a pregnancy, you should consult her doctor to make sure she can tolerate it, because very severe disease can make the pregnancy dangerous for her. If her disease isn’t so severe, usually there are no special problems.

Q. Can cystic fibrosis patients have children? My boyfriend has cystic fibrosis, and currently he’s treated with many medications but usually healthy (other than pneumonia from hospitalization from time to time). I heard that men with cystic fibrosis can’t have children - is that true? Is there anything he can do about it?

A. WE ARE A HEALTHY COUPLE BUT MY WIFE NEVER GET PREGNANT IN 20 YEARS OF RELATIONSHIP.
I'M SO SORRY ABOUT MY ENGLISH, I'M LEARNING.

Q. my uncle was diagnosed with pulmonary fibrosis. can anyone help?

A. Pulmonary Fibrosis involves scarring of the lung. Gradually, the air sacs of the lungs become replaced by fibrotic tissue. When the scar forms, the tissue becomes thicker causing an irreversible loss of the tissue’s ability to transfer oxygen into the bloodstream. Traditional theories have postulated that it might be an autoimmune disorder, or the after effects of an infection, viral in nature. There is a growing body of evidence which points to a genetic predisposition. A mutation in the SP-C protein has been found to exist in families with a history of Pulmonary Fibrosis. The most current thinking is that the fibrotic process is a reaction to microscopic injury to the lung. While the exact cause remains unknown, associations have been made with the following:*Inhaled environmental and occupational pollutants, *Cigarette smoking, *Diseases such as Scleroderma, Rheumatoid Arthritis, Lupus,*Therapeutic radiation. For full: http://www.pulmonaryfibrosis.org/ipf.htm Hope this helps.

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Moreover, the stroma associated with hyperplastic ducts showed signs of desmoplasia and contained an increased number of mast cells, suggesting a heightened risk of neoplastic transformation.
2,3 In addition, PDAC tumors often exhibit a high degree of desmoplasia, characterized by a fibrotic connective tissue stroma, the extent of which has been found to correlate with CTGF levels.
 
 
 
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