desipramine


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desipramine

 [des-ip´rah-mēn]
a tricyclic antidepressant of the dibenzazepine group, administered orally as the hydrochloride salt.

desipramine

/de·sip·ra·mine/ (des-ip´rah-mēn) a tricyclic antidepressant of the dibenzazepine class; used as the hydrochloride salt.

desipramine

(dĭ-zĭp′rə-mēn, dĕz′ə-prăm′ĭn)
n.
A tricyclic antidepressant drug, C18H22N2, used in its hydrochloride form.

desipramine

Norpramin®, Pertofran Therapeutics An imipramine-like tricyclic antidepressant. See Imipramine.

desipramine

a tricyclic antidepressant.
References in periodicals archive ?
A significant reduction in immobility time in the TST was observed in the mice treated with YZ-30 and YZ-50, similar to the positive control desipramine, indicating a significant antidepressant-like effect.
The rats were pretreated 30 minutes before the 6-OHDA infusion with 25 mg/kg intraperitoneal desipramine (Sigma) to protect noradrenergic projections.
KEY WORDS: desipramine, plasma neurotransmitters, neural sympathetic activity, adrenal sympathetic activity
Research also suggests that adding desipramine or high-dose tiagabine to an opioid agonist maintenance regimen can be helpful.
Norpramin is the brand name for an antidepression drug containing desipramine.
Antidepressants were amitriptyline, bupropion, citalopram, desipramine, doxepin, venlafaxine, imipramine, fluoxetine, paroxetine, trazodone, sertraline, amoxapine, and fluvoxamine.
5 Citalopram (Celexa) 20 20-60 Escitalopram (Lexapro) 10 10-20 TCAs Amitriptyline (Elavil) 25 tid 100-300 * Clomipramine (Anafranil) 25 100-250 Desipramine (Norpramin) 25 100-300 Nortriptyline (Pamelor, Aventyl) 25 tid-qid 50-150 Imipramine (Tofranil) 25 100-300 * SNRIs Venlafaxine XR Immediate-release (Effexor) 37.
dependent and was not observed in the presence of imipramine or desipramine, serotonin (SERT) and norepinephrine transporter (NET) blockers, indicating it was specific for uptake blocker binding.
A postmortem ruled that the child died from the toxic effects of Desipramine, a psychoactive drug she had been compelled to take after a school psychiatrist suggested she suffered from Attention Deficit Hyperactivity Disorder (ADHD).
Tricyclic anti-depressants such as desipramine (Norpramin), imipramine (Tofranil), nortriptyline (Pamelor), amytripty- line (Elavil) as well as buproprion (Wellbutrin), a dopamine reuptake blocker, are sometimes used to treat depression as well as inattention, impulsivity and hyperactivity (attention deficit hyperactivity disorder symptoms-ADHD) in the non-autistic population.
desipramine, nortriptyline) exhibit fewer anticholinergic and sedative effects than the tertiary amines (e.