A significant reduction in immobility time in the TST was observed in the mice treated with YZ-30 and YZ-50, similar to the positive control desipramine
, indicating a significant antidepressant-like effect.
Treatment--behavioural and pharmacological (for excessive sleepiness and cataplexy) Behavioural Ensure good sleep hygiene (avoid sleep deprivation) Consider use of strategic napping Pharmacological: For excessive sleepiness Methylphenidate Amphetamine Modafinil Selegiline (also anti-cataplectic) Pharmacological: For cataplexy Gamma-hydroxybutyric acid/sodium oxybate Protriptyline Desipramine
Imipramine Clomipramine Venlafaxine Duloxetine Selective serotonin reuptake inhibitors
The rats were pretreated 30 minutes before the 6-OHDA infusion with 25 mg/kg intraperitoneal desipramine
(Sigma) to protect noradrenergic projections.
KEY WORDS: desipramine
, plasma neurotransmitters, neural sympathetic activity, adrenal sympathetic activity
Research also suggests that adding desipramine
or high-dose tiagabine to an opioid agonist maintenance regimen can be helpful.
I am currently taking Desipramine
on a trial basis.
imipramine and desipramine
, are effective in controlling behaviour and improving cognitive impairments but are less effective than the stimulants.
Some of the most frequently prescribed tricyclics are amitriptyline (Elavil), desipramine
(Norpramin), clomipramine (Anafranil), doxepin (Sinequan), imipramine, (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil) and trimipramine (Surmontil).
Effects of desipramine
on irritable bowel syndrome compared with atropine and placebo.
xx Aventyl, Budeprion SR, bupropion, Celexa, clomipramine, desipramine
, Desyrel, Effexor, Effexor XR, Elavil, Emitrip, fluoxetine, fluvoxamine maleate, imipramine, Lexapro, Ludiomil, Luvox, maprotiline, mirtazapine, nefazodone, Norpramin, nortriptyline, Pamelor, paroxetine, Paxil, Paxil CR, Pexeva, Prozac, Prozac Weekly, Remeron, Serzone, Surmontil, Tofranil, Tofranil-PM, Trazodone, Vivactil, Wellbutrin, Wellbutrin SR, Wellbutrin XL, Zoloft Diabetes 250.
Decrease in brain serotonin-2 receptor binding in patients with major depression following desipramine
treatment: a positron emission tomography study with fluorine-18-labeled setoperone.
Examples include doxepin (Adapin, Sinequan), amitriptyline (Elavil), desipramine
(Norpramin) and nortriptyline (Pamelor).