desferrioxamine


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desferrioxamine

/des·fer·ri·ox·amine/ (des-fer´e-oks´ah-mēn) deferoxamine.

desferrioxamine

An iron CHELATING AGENT used in iron overload conditions or iron poisoning. A brand name is Desferal.

desferrioxamine

see deferoxamine.

deferoxamine, desferrioxamine

an iron chelating compound used as the mesylate to treat iron poisoning.
References in periodicals archive ?
Protective effects of thymoquinone and desferrioxamine against hepatotoxicity of carbon tetrachloride in mice.
Cheah SF, Kraemer SM, Cervini-Silva J, Sposito G (2003) Steady-state dissolution kinetics of goetbite in the presence of desferrioxamine B and oxalate ligands: implications for the microbial acquisition of iron.
We compared 2 NTBI assays: a labile plasma iron (LPI) assay that uses desferrioxamine as the iron chelator (3) and a microwell modification of a bleomycin-detectable iron (BDI) assay (2).
All buffers were supplemented with the deaminase inhibitors coformycin (5 [micro]g/mL) (National Cancer Institute, Bethesda, MD) and tetrahydro-uridine (50 [micro]g/mL) (Calbiochem, San Diego, CA), and the antioxidant desferrioxamine (0.
61) In patients with thalassemia major, who have massive iron accumulations as a result of multiple transfusions, 140 mg three times per day of the milk thistle component silymarin enhanced the iron-chelating effects of the drug desferrioxamine.
Aluminium can be removed from the body by taking desferrioxamine, a trivalent ion chelator.
Heavy metal sorption on soil minerals affected by the siderophore desferrioxamine B: the role of Fe (III) (hydr)oxides and dissolved Fe (III).
Iron overload may be treated or prevent with a chelating agent such as desferrioxamine (DFO) which is capable of complexing with iron and promoting its excretion.
Clinical experience with desferrioxamine in dialysis patients with aluminum toxicity.
Intramuscular desferrioxamine in patients with Alzheimer's disease.
Possible protective effect of melatonin and/or desferrioxamine against streptozocin-induced hyperglycaemia in mice.
Key: SLE = Systemic lupus erythematosus Generic Name Trade Name Indication Toxic retinopathy Plaquenil Hydroxychloroquine Rheumatoid arthritis, SLE Tamoxyfen Nolvadex Breast cancer Vigabatrin Sabril Epilepsy anti-convulsant Chlorpromazine Largactil Anti-psychotic Desferrioxamine Desferal Anaemia Toxic optic neuropathy Ethambutol Isoniazid Rifina- Tuberculosis treatment Generic Name Visual side effect Toxic retinopathy Plaquenil Bull's eye maculopathy - blurred vision, altered colour Tamoxyfen Crystalline maculopathy - vision impaired if severe Vigabatrin Field restriction Chlorpromazine Blurred vision, abnormal colour (brownish tinge) Desferrioxamine Acuity reduction, scotomata, photopsia, metamorphopsia Toxic optic neuropathy Ethambutol Isoniazid Acuity and field loss, colourdefect-