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dermatofibrosis

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dermatofibrosis
a syndrome inherited as a dominant trait in German shepherd dogs in which multiple, firm cutaneous and subcutaneous nodules of mature fibrous tissue, up to 2 inches in diameter, develop in middle age. Affected animals show a high incidence of renal adenocarcinoma and females have multiple uterine and vaginal leiomyomas. Called also nodular dermatofibrosis.


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1,2) Several clinical abnormalities associated with OPK have been reported, including rheumatoid arthritis, synovial chondromatosis, and, more frequently, dermatological pathologies (such as dermatofibrosis lenticularis disseminata, keloid formations and scleroderma-like lesions).
 
 
 
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