A clinical diagnosis of dermatofibrosarcoma
protuberans was made.
It differs from other fibrous conditions such as fibromatosis, juvenile aponeurotic fibroma, subepidermal nodular fibrosis, and dermatofibrosarcoma
However, p16 overexpression has also been identified in other neoplasms that have not been shown to be HPV related, including dermatofibrosarcoma
protuberans, gastric adenocarcinomas, serous endometrial carcinomas, and Hodgkin and non-Hodgkin lymphomas.
protuberans (DFSP) is an uncommon, fibrohistiocytic tumour known to be locally invasive and with very low incidence of distant metastasis (1).
Hamish McMurdo gave a patient's perspective on surviving dermatofibrosarcoma
protuberans of the occipital bone.
Furthermore, imatinib is approved for the treatment of adult patients with newly diagnosed Philadelphia chromosome positive acute lymphoblastic leukaemia (Ph+ ALL) integrated with chemotherapy, adult patients with relapsed or refractory Ph+ ALL as monotherapy, adult patients with myelodysplastic/myeloproliferative diseases (MDS/MPD) associated with platelet-derived growth factor receptor (PDGFR) gene re-arrangements, adult patients with advanced hypereosinophilic syndrome (HES) and/or chronic eosinophilic leukaemia (CEL) with FIP1L1-PDGFR alpha rearrangement and the treatment of adult patients with unresectable dermatofibrosarcoma
protuberans (DFSP) and adult patients with recurrent and/or metastatic DFSP who are not eligible for surgery.
KS--by far the most common form of CSTS worldwide--accounted for 71% of cases, followed by dermatofibrosarcoma
protuberans (18%), malignant fibrous histiocytoma (5.
The company says the diseases found to have Gleevec-sensitive pathways include the solid tumor dermatofibrosarcoma
protuberans, and three hematologic diseases - certain forms of myeloprolifterative disorders, hypereosinophilic syndrome, and systemic mastocytosis.
Additionally, recurrences have been noted in lesions with ambiguous immunohistochemistry staining patterns, which some authors cite as evidence for the concept of a biologic spectrum between dermatofibroma and dermatofibrosarcoma
ABSTRACT: A female patient with progressive systemic sclerosis and pulmonary fibrosis had a dermatofibrosarcoma
protuberans on the right thigh.
Imatinib indications: Chronic myeloid leukemia; acute lymphoblastic leukemia; Kit (CD117)-positive malignant gastro-intestinal stromal tumours (GIST); dermatofibrosarcoma
5] The differential diagnosis for melanin in cancer cell usually leads to the diagnosis of melanoma, melanotic neurofibroma, melanotic dermatofibrosarcoma
protuberans, pheochromocytoma, basal cell carcinoma, seborrhetic keratosis or breast cancer.