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dermal toxicity

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dermal toxicity,
n an adverse skin reaction to the application of essential oils and other substances; includes irritation, (inflammation, itching) sensitization (reactions occurring after initial contact), and phototoxicity, (increased vulnerability to sun).


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EPA (1998), the acute oral toxicity (lethal dose) of QpE in rats is estimated at 1,480 and 1,670 mg/kg for females and males, respectively; dermal toxicity is > 5,000 mg/kg, and inhalation toxicity (lethal concentration) is 5.
PCDD and PCDF are toxic and persistent chemicals whose effects on human health and the environment include dermal toxicity, immunotoxicity, reproductive effects and teratogenicity, endocrine disrupting effects and carcinogenicity.
Different sections cover skin structure and function, principles and measurement of skin absorption, clinical aspects of dermal toxicity and in vitro alternatives.
 
 
 
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