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derepression

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.10 sec.
derepression /de·re·pres·sion/ (de″re-presh´un) removal of repression, such as of an operon so that gene transcription occurs or is enhanced, with the net result frequently being elevation of the level of a specific enzyme.
de·re·pres·sion (dr-prshn)
n.
The activation of an operator gene by the deactivation of a repressor gene.

dere·press (-prs) v.

derepression
1. elevation of the level of an enzyme above the normal, either by lowering the corepressor concentration or by a mutation that decreases the formation of aporepressor or the response to the complete repressor.
2. the inhibition of the repressor substance produced by the regulator genes with the result that the operator gene is free to initiate the process of polypeptide formation.


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2003), as these genes may be activated through Sp1 derepression (Ogra et al.
 
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