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An oligo- or polypeptide containing one or more ester bonds as well as peptide bonds.
See also: peptolide.
[G. deseō, to knead, blend, + peptide]
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Peptide Segment Covered In Repor t: Cyclic-Peptide, Polypeptide, Glycopeptide, Glycopeptide, Oligopeptide, Depsipeptide, Neuropeptide, Dipeptides, Natriuretic Peptide, Lipopeptide, Opioid Peptide, Peptide Vaccine, Antimicrobial Cationic Peptide & Insulin Global Peptide Therapeutics Pipeline Insight 2015 Report Highlights: - Global Peptide Therapeutics Market Overview - Global Peptide Therapeutics Pipeline By Peptide Type - Global Peptide Therapeutics Pipeline By Company, Indication & Phase - Peptide Therapeutics Clinical Pipeline: 743 Peptides - Majority Peptide Therapeutics in Preclinical Phase: 293 Peptides - Commercially available Peptides: 126 Peptides Key Topics Covered: 1.
A phase I and pharmacodynamic study of depsipeptide (FK228) in chronic lymphocytic leukemia and acute myeloid leukemia.
Cardiovascular Toxicity of Selected Chemotherapy Agents Acute Coronary Heart Failure Hypertension Syndromes QTc Prolongation Anthracyclines Bevacizumab Fluorouracil Arsenic trioxide Trastuzumab Sorafenib Bevacizumab Depsipeptide Lapatinib Sunitinib Sorafenib Sunitinib Alemtuzumab VDAs * VDAs Dasatinib VDAs * Vascular disrupting agents Source: Dr.
HDAC LAQ824 Histone deacetylase Phase I/II inhibition SAHA inhibitors reduce HER2 [78,80,81] PXD101 protein expression and Depsipeptide block PI3K/Akt and CI-994 MAPK signalling.
Characterization of Tn1546, a Tn3-related transposon conferring glycopeptide resistance by synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147.
of the National Cancer Institute (NCI), in a poster session entitled "Update on The Phase 2 Trial and Correlative Studies of Depsipeptide in Patients with Cutaneous T-Cell Lymphoma (CTCL) and Relapsed Peripheral T-Cell Lymphoma (PTCL)," at the Annual Meeting of the American Society of Clinical Oncology.
Ueda H, Manda T, Matsumoto S, Mukumoto S, Nishigaki F, Kawamura I, Shimomura K (1994) FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No.
Abstract #5372 - Synergy of Histone Deacetylase Inhibitors, Belinostat and Depsipeptide, With DNA Damaging Agents, Etoposide and Cisplatin, In Small Cell Lung Cancer Cell Lines
Molecular basis of vancomycin resistance in Enterococcus faecium BM4147: biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA.
Kahalalide F is a depsipeptide derived from the sea slug Elysia rufescens.