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deoxyuridine

   Also found in: Wikipedia 0.01 sec.
deoxyuridine /de·oxy·uri·dine/ (-ūr´ĭ-dēn) a pyrimidine nucleoside, uracil linked to deoxyribose; its triphosphate derivative is an intermediate in the synthesis of deoxyribonucleotides.
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A further method that can limit contamination is where the amplicon can be inactivated by incorporating deoxyuridine (dUTP) instead of dTTP in the PCR assay, so that any amplicons that may contaminate subsequent assays are cleaved by uracil-N-glycosylase (9).
Review of molecular methods for medical microbiology testing by Evans, Gloria / New Zealand Journal of Medical Laboratory Science
78) The production of thymidine monophosphate (TMP) via the salvage route supplements de novo synthesis from intracellular deoxyuridine such that the rate of uptake of exogenous TdR or FLT is affected by the relative utilization of the salvage versus de novo pathways.
The role of PET in the management of brain tumors by Spence, Alexander M.; Mankoff, David A.; Muzi, Mark / Applied Radiology
In addition, terminal deoxynucleotide transferase-mediated deoxyuridine triphosphate nick-end labeling (TUNEL)-positive cells are colocalized with FasL in MS lesions.
Oligodendrocyte cell death in pathogenesis of multiple sclerosis: ... by Cudrici, Cornelia; Niculescu, Teodora; Niculescu, Florin; Shin, Moon L.; Rus, Horea / Journal of Rehabilitation Research & Development
 
 
 
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