deoxyribonuclease I


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de·ox·y·ri·bo·nu·cle·ase I

, DNase I [MIM*125505]
an endonuclease that cleaves primarily double-stranded DNA to a mixture of oligodeoxyribonucleotides, each ending in a 5'-phosphate; streptodornase is a similar enzyme. Under appropriate conditions, it can produce single-strand nicks in DNA; used in nick translation and in the mapping of hypersensitive sites.
References in periodicals archive ?
Limited Tenders are invited for Supply of Chemicals and Antibodies, Anti-phospho-Insulin Receptor/Insulin-Like Growth Factor-1 Receptor, Genelute Direct mRNA Miniprep Kit, First strand synthesis kit, RNAseZAP, Deoxyribonuclease I kit, Sephadex, etc.
Human serum deoxyribonuclease I (DNase I) polymorphism: pattern similarities among isozymes from serum, urine, kidney, liver, and pancreas.
Measurement of deoxyribonuclease I activity in human tissues and body fluids by a single radial enzyme-diffusion method.
An abrupt elevation of the serum deoxyribonuclease I (DNase I) activity in acute myocardial infarction [Abstract].