deoxyribonuclease


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Related to deoxyribonuclease: Deoxyribonucleic

deoxyribonuclease

 (DNase) [de-ok″sĭ-ri″bo-nu´kle-ās]
an enzyme that catalyzes the hydrolysis (depolymerization) of deoxyribonucleic acid (DNA).

de·ox·y·ri·bo·nu·cle·ase (DNAse, DNAase, DNase),

(de-oks'ē-rī'bō-nū'klē-ās),
Any enzyme (phosphodiesterase) hydrolyzing phosphodiester bonds in DNA.
See also: endonuclease, nuclease.

deoxyribonuclease

/de·oxy·ri·bo·nu·cle·ase/ (DNase) (-ri″bo-noo´kle-ās) any nuclease catalyzing the cleavage of phosphate ester linkages in deoxyribonucleic acids (DNA); separated by whether they cleave internal bonds or bonds at termini.

deoxyribonuclease

(dē-ŏk′sē-rī′bō-no͞o′klē-ās′, -āz′, -nyo͞o′-)
n.
DNase.

APEX1

A gene on chromosome 14q11.2 that encodes a major apurinic/apyrimidinic (AP) endoDNAase, which is involved in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents, and in the redox regulation of transcriptional factors.

de·ox·y·ri·bo·nu·cle·ase

(DNase) (de-oks'ē-rī'bō-nū'klē-ās)
Any enzyme (phosphodiesterase) hydrolyzing phosphodiester bonds in DNA.
See also: endonuclease, nuclease

deoxyribonuclease

An enzyme that cuts DNA strands by breaking PHOSPHODIESTER BONDS.

deoxyribonuclease (DNAse)

see NUCLEASE.

deoxyribonuclease

an enzyme that catalyzes the hydrolysis (depolymerization) of deoxyribonucleic acid (DNA). Abbreviated DNase.
References in periodicals archive ?
The relationship of deoxyribonuclease inhibitor levels in human sera to the occurrence of antinuclear antibodies.
Human serum deoxyribonuclease I (DNase I) polymorphism: pattern similarities among isozymes from serum, urine, kidney, liver, and pancreas.
Measurement of deoxyribonuclease I activity in human tissues and body fluids by a single radial enzyme-diffusion method.
An abrupt elevation of the serum deoxyribonuclease I (DNase I) activity in acute myocardial infarction [Abstract].
E6 and E7 in apoptosis: Apoptosis is a genetically determined program, which leads to the induction of caspase activated deoxyribonucleases (Fig.
9,25) Deoxyribonucleases (DNases) are enzymes that hydrolyse, or break down, the phosphodiester bonds between the nucleotides in a strand of DNA.
These results support the notion that use of formaldehyde to inhibit enzymes that destroy DNA, such as deoxyribonucleases, can be eliminated.
Plasma deoxyribonucleases are known to exist, but their activity in vitro at room temperature is not well characterized.

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