deoxycholic acid


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deoxycholic acid

 [de-ok″sĭ-ko´lik]
a secondary bile acid, capable of forming soluble, diffusible complexes with fatty acids, and thereby allowing for their absorption in the small intestine.

de·ox·y·cho·lic ac·id

(dē-oks'ē-kō'lik as'id),
7-Deoxycholic acid; 3α,12α-dihydroxy-5β-cholanic acid; a bile acid and choleretic; used in biochemical preparations as a detergent.

deoxycholic acid

/de·oxy·chol·ic ac·id/ (de-ok″se-ko´lik) a secondary bile acid formed from cholic acid in the intestine; it is a choleretic.

de·ox·y·cho·lic ac·id

(dē-oks'ē-kō'lik as'id)
A bile acid and choleretic; used in biochemical preparations as a detergent.

deoxycholic acid

one of the bile acids, capable of forming soluble, diffusible complexes with fatty acids, and thereby allowing for their absorption in the small intestine.
References in periodicals archive ?
A Double-blind, Placebo-controlled, Phase 3b Safety Study of Deoxycholic Acid Injection (ATX-101) for Reduction of Submental Fat in Subjects with Mild or Extreme Submental Fullness"
Therefore, the adsorption capacities of high-molecular-weight CS and its stearale toward deoxycholic acid sah were investigated in this study.
Three of the bile acids alone (chenodeoxycholic acid, deoxycholic acid and cholic acid) and the combination of all 4 showed inhibition of growth at 2 and 8 weeks.
Prolonged large bowel transit is associated with an increase in input rate and pool size of deoxycholic acid.
Additionally, lithocholic acid and deoxycholic acid were noted as the major bile-acid components; both this and the 5[Beta]-stanol distribution, dominated by coprostanol, attested to a human source.
Deoxycholic acid is the best known and most studied bile acid when it comes to cancer-causing ability, according to the Arizona researcher.
Its urso deoxycholic acid can aid in treating liver ailments.
Consumption of some polyphenols reduces fecal deoxycholic acid and lithocholic acid, the secondary bile acids of risk factors of colon cancer.
The farnesoid X receptor (FXR) is a receptor for bile acids such as chenodeoxycholic acid (CDCA), deoxycholic acid, cholic acid, and their conjugates.
New patent covering synthetic deoxycholic acid will expand intellectual property protection for ATX-101