deoxycholic acid


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deoxycholic acid

 [de-ok″sĭ-ko´lik]
a secondary bile acid, capable of forming soluble, diffusible complexes with fatty acids, and thereby allowing for their absorption in the small intestine.

de·ox·y·cho·lic ac·id

(dē-oks'ē-kō'lik as'id),
7-Deoxycholic acid; 3α,12α-dihydroxy-5β-cholanic acid; a bile acid and choleretic; used in biochemical preparations as a detergent.

deoxycholic acid

/de·oxy·chol·ic ac·id/ (de-ok″se-ko´lik) a secondary bile acid formed from cholic acid in the intestine; it is a choleretic.

de·ox·y·cho·lic ac·id

(dē-oks'ē-kō'lik as'id)
A bile acid and choleretic; used in biochemical preparations as a detergent.

deoxycholic acid

one of the bile acids, capable of forming soluble, diffusible complexes with fatty acids, and thereby allowing for their absorption in the small intestine.
References in periodicals archive ?
He participated in phase III testing of deoxycholic acid.
CSC bound more deoxycholic acid salt than CS at the identical pH, which can be attributed to the increased hydrophobicity after CS combined the long carbon chain of stearic acid.
These included a deoxycholic acid culture at 8 mg/ml and 3 cholic acid cultures with the following concentrations: 16 mg/ml, 8 mg/ml and 4 mg/ml.
Patent and Trademark Office (USPTO) for a patent application that claims synthetic deoxycholic acid or pharmaceutically acceptable salts thereof, including the synthetic form that is used in ATX-101, a potential first-in-class, injectable drug under clinical investigation for the reduction of submental fat, which commonly presents as an undesirable "double chin.
However, applicators tend to be "one size fits all," so if it doesn't work for a patient, the procedure would have to be done with deoxycholic acid.
including two European patents that cover non-surgical methods of removing localized fat accumulation using deoxycholic acid.
Niamtu shared tips and techniques for best results using deoxycholic acid (Kybella) injection for reduction of submental fat, based on several months of real-world use since it was approved in 2015.
CHICAGO -- Deoxycholic acid injections benefit patients on either end of the spectrum with mild or extreme submental fat, a phase III safety study shows.
There are reports of temporary alopecia of the beard area in men after deoxycholic acid (Kybella) injections in the submentum.
ATX-101 is a proprietary formulation of nonhuman, nonanimal deoxycholic acid.
It is a synthetic form of naturally occurring deoxycholic acid (DCA), which lyses adipocytes when properly injected into subcutaneous fat.
ATX-101 is a proprietary formulation of a purified synthetic version of deoxycholic acid, a naturally occurring molecule in the body that aids in the breakdown of dietary fat.