The end of the Neolithic was also a period of considerable transformation, leading into the Early Copper Age (4500-4000 cal BC), a period of denucleation
as the largest settlements were abandoned for a more dispersed settlement pattern of smaller and more homogeneous sites, indicating a breakdown in the settlement hierarchy and a reorganisation of community bonds.
Therefore, facticity is to be radically distinguished from the stable presence (Vorhandenheit) or fullness of being in the unity of the one by the movement of its own factical denucleation
or dispersion into the manifold.
In these preclinical bench studies, BioDisc provided stability over denucleation
alone and preserved range of motion.
of intervertebral discs is a common treatment for lower back pain that involves the surgical removal of damaged or diseased disc materials resulting in motion destabilization and progressive reduction in disc height.
In this respect, Thio apparently stands far from the social and cultural denucleation
process and village death--in our context the tribe or emic village (50)--that Tuzin (1988) observed in another western Pacific context.
The process simply involves denucleation
of an oocyte (removal of the metaphase plate) through micro-manipulation.