dentin dysplasia


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Related to dentin dysplasia: dentinogenesis imperfecta, amelogenesis imperfecta, Regional odontodysplasia

den·tin dys·pla·si·a

a hereditary disorder of the teeth, involving both primary and permanent dentition, in which the clinical morphology and color of the teeth are normal, but the teeth radiographically exhibit short roots [MIM 125400], obliteration of the pulp chambers and canals, mobility, and premature exfoliation; autosomal dominant inheritance. In another type of dentin disease the teeth are opalescent [MIM 125420].

dentinogenesis imperfecta

A common (1 in 6–8,000) inherited disorder of tooth development (OMIM:125490), which is characterised by blue-gray or yellow-brown translucencies of the teeth.

Molecular pathology
Dentinogenesis imperfecta is caused by mutations of DSPP, the gene that encodes two key proteins of the dentin extracellular matrix: dentin sialoprotein and dentin phosphoprotein.

den·tin dys·pla·si·a

(den'tin dis-plā'zē-ă)
A hereditary disorder of the teeth, involving both primary and permanent dentition, in which the clinical morphology and color of the teeth are normal, but the teeth radiographically exhibit short roots, obliteration of the pulp chambers and canals, mobility, and premature exfoliation.

den·tin dys·pla·si·a

(den'tin dis-plā'zē-ă)
Hereditary tooth disorder involving both primary and permanent dentition, in which the clinical morphology and color of the teeth are normal, but the teeth radiographically exhibit short roots, obliteration of the pulp chambers and canals, mobility, and premature exfoliation.