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denervation hypersensitivity

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denervation hypersensitivity (dē·ner·vāˑ·shn hīˈ·per·senˈ·si·tiˑ·vi·tē),
n interruption of automatic innervation to an organ, following which the degradative enzymes at the site are lost; as a result, the synaptic receptor becomes extremely sensi-tive to the neurohumoral agent because of loss of the degradative mechanism.

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Garibaldi et al proposed that the resolution of ptosis by apraclonidine occurs as a result of denervation hypersensitivity of the [[alpha].
 
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