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denervation hypersensitivity

   Also found in: Encyclopedia 0.01 sec.
denervation hypersensitivity (dē·ner·vāˑ·shn hīˈ·per·senˈ·si·tiˑ·vi·tē),
n interruption of automatic innervation to an organ, following which the degradative enzymes at the site are lost; as a result, the synaptic receptor becomes extremely sensi-tive to the neurohumoral agent because of loss of the degradative mechanism.


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Denervation hypersensitivity or increased sensitivity to particular circulating hormones in blood is also possible, and this causes the failure of this surgical procedure.
Garibaldi et al proposed that the resolution of ptosis by apraclonidine occurs as a result of denervation hypersensitivity of the [[alpha].
 
 
 
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