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denervation |
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denervation /de·ner·va·tion/ (de?ner-va´shun) interruption of the nerve connection to an organ or part. denervation (de´nurvā´sh n the sectioning or removal of a nerve to interrupt the nerve supply to a part. denervation interruption of the nerve connection to an organ or part. denervation atrophy reduction in muscle fiber diameter as a result of discontinuation of nerve supply; always accompanied by paralysis; also called neurogenic atrophy. |
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66-68) Animal studies (66,67) suggest that denervation and mechanoreceptor loss actually precede joint degeneration and may potentially be a causative factor in knee OA. Botulinum toxin, which causes temporary chemical denervation of the cholinergic nerve fibers, has also been used successfully to manage sialoceles. Expression of these channels can be regulated during development by many factors, including enervation and denervation of muscle fibers and coexpression of [beta] subunits with their [alpha]-subunit counterparts. |
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