demyelinating optic neuritis

demyelinating optic neuritis

An acute inflammation of an optic nerve associated with a drop in visual acuity and colour perception, pain on movement of the eye, a dull periorbital ache and a poor pupil response to direct light. The optic disk may or may not be visibly swollen. This is the presenting feature in 15 to 20 percent of patients with MULTIPLE SCLEROSIS and it occurs in 50 percent of patients with the disease.
References in periodicals archive ?
1) Other conditions can present with acute unilateral vision loss and a swollen optic disc, such as demyelinating optic neuritis or sarcoidosis, so a thorough medical evaluation is required.
There is too little information on the early histologic changes of acute demyelinating optic neuritis as a manifestation of multiple sclerosis or neuromyelitis optica for definitive guidance in the differential diagnosis of ION.
The patients who had acute demyelinating optic neuritis were treated with intravenous methylprednisolone 30 mg/kg/day for 3 days followed by 11 days of oral prednisolone 1 mg/kg/day for 11 days as per the Optic Neuritis Treatment Protocol.
In most parts of the world acute demyelinating optic neuritis (ON) is the most common cause of unilateral painful visual loss in a young adult.
The most common form of optic neuritis is acute demyelinating optic neuritis.
The clinical diagnosis of acute demyelinating optic neuritis is based on medical history and clinical features (106), so when faced with a patient with idiopathic demyelinating optic neuritis, ophthalmologists should consider the following: