demyelinating diseases


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demyelinating diseases

Diseases that feature loss of the myelin sheath of nerve fibres in the white matter of the central nervous system. The most important of the demyelinating diseases is MULTIPLE SCLEROSIS. Others include acute demyelinating encephalomyelitis, which may follow measles or chickenpox, and neuromyelitis optica, in which both optic nerves are affected as well as the spinal cord.

demyelinating diseases

group of central and peripheral nervous system disorders characterized by progressive and/or segmental demyelination of nerves and resultant loss of neurological function, e.g. multiple sclerosis, diabetes mellitus
References in periodicals archive ?
7-11, 16-18) Although we cannot exclude the possibility of a primary process involving the peripheral vestibular neuroepithelial cells, our findings--particularly our finding of demyelination with axon sparing--are highly suggestive of an active primary demyelinating disease process that might be of immune-mediated origin.
Although it is still uncertain whether we can transform these observations into a therapy, our research team has provided the first indications of a new pathway that may enable us to repair the nerve damage found in patients afflicted by MS and other serious demyelinating diseases.
More long-term studies examining bigger patient series should be performed to enlighten the relationship between demyelinating diseases and IBD.
Every case with suspected demyelinating disease involving the spinal cord should be complemented with brain MRI.
However, there is a suggestion of relapse of demyelinating diseases following surgery (2,3).
Demyelinating diseases such as multiple sclerosis (MS) or acute disseminated encephalomyelitis are also diagnostic possibilities.
Analysis through week 48 showed there were no deaths and no cases of opportunistic infections, tuberculosis, demyelinating diseases, hematologic events, or congestive heart failure.
said that although PML and MS are both demyelinating diseases, the mechanisms of demyelination are different and PML is "not at all related to MS," he said.
Other CNS demyelinating diseases occur as a consequence of infection of the CNS (eg, progressive multifocal leukoencephalopathy, subacute sclerosing panencephalitis, and progr essive rubella panencephalitis).
A thorough examination of chronic inflammatory and demyelinating diseases has been enhanced.
In June 1985, BC/BS updated its assessment and recommended that MRI be considered" generally accepted medical practice for diagnostic conditions of the posterior fossa (cerebellum and brainstem) and high (C1 through C4) cervical cord and demyelinating diseases of the white matter of the brain.
It also reviews key players involved in the therapeutic development for Demyelinating Diseases.