7-11, 16-18) Although we cannot exclude the possibility of a primary process involving the peripheral vestibular neuroepithelial cells, our findings--particularly our finding of demyelination with axon sparing--are highly suggestive of an active primary demyelinating disease
process that might be of immune-mediated origin.
Although it is still uncertain whether we can transform these observations into a therapy, our research team has provided the first indications of a new pathway that may enable us to repair the nerve damage found in patients afflicted by MS and other serious demyelinating diseases
More long-term studies examining bigger patient series should be performed to enlighten the relationship between demyelinating diseases
Every case with suspected demyelinating disease
involving the spinal cord should be complemented with brain MRI.
However, there is a suggestion of relapse of demyelinating diseases
following surgery (2,3).
such as multiple sclerosis (MS) or acute disseminated encephalomyelitis are also diagnostic possibilities.
Analysis through week 48 showed there were no deaths and no cases of opportunistic infections, tuberculosis, demyelinating diseases
, hematologic events, or congestive heart failure.
said that although PML and MS are both demyelinating diseases
, the mechanisms of demyelination are different and PML is "not at all related to MS," he said.
Other CNS demyelinating diseases
occur as a consequence of infection of the CNS (eg, progressive multifocal leukoencephalopathy, subacute sclerosing panencephalitis, and progr essive rubella panencephalitis).
A thorough examination of chronic inflammatory and demyelinating diseases
has been enhanced.
In June 1985, BC/BS updated its assessment and recommended that MRI be considered" generally accepted medical practice for diagnostic conditions of the posterior fossa (cerebellum and brainstem) and high (C1 through C4) cervical cord and demyelinating diseases
of the white matter of the brain.
It also reviews key players involved in the therapeutic development for Demyelinating Diseases