Hepatitis delta virus genotypes I and II cocirculate in an endemic area of Yakutia, Russia.
Chronic hepatitis delta virus infection with genotype lib variant is correlated with progressive liver disease.
Hepatitis delta virus is the only representative of the Deltavirus genus, which consists of 7 differentiated major clades.
Hepatitis delta virus (HDV) is a subviral agent that can lead to severe acute and chronic forms of liver disease in association with hepatitis B virus.
Molecular phylogenetic analyses indicate a wide and ancient radiation of African hepatitis delta virus, suggesting a deltavirus genus of at least seven major clades.
Genotype-specific complementation of hepatitis delta virus RNA replication by hepatitis delta antigen.
His primary research interest is the genetic diversity of HDV and its consequences on the epidemiology of delta virus and on diagnostic applications.
Feb 23, 2015: Eiger BioPharmaceuticals Announces Presentation of Positive Data in Patients Infected with Hepatitis Delta Virus (HDV) Treated with Lonafarnib
Dec 22, 2014: Eiger Bio Announces Positive Data in Patients Infected with Hepatitis Delta Virus (HDV) Treated with Lonafarnib - Results Presented at American Association for the Study of Liver Diseases (AASLD) Meeting
Dec 22, 2014: Eiger Bio Receives Orphan Designation for Lonafarnib, a First In Class, Investigational Treatment for Hepatitis Delta Virus (HDV) Infection