deletion


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Related to deletion: deletion syndrome, Deletion mutation

deletion

 [de-le´shun]
in genetics, loss of genetic material from a chromosome.
 Examples of large-scale chromosomal deletions: A, terminal; B, interstitial. From Dorland's, 2000.

de·le·tion

(dĕ-lē'shŭn),
In genetics, any spontaneous elimination of part of the normal genetic complement, whether cytogenetically visible (chromosomal deletion) or found by molecular techniques.
[L. deletio, destruction]

deletion

/de·le·tion/ (dĕ-le´shun) in genetics, loss of genetic material from a chromosome.
Examples of large-scale chromosomal deletions: (A), terminal; (B), interstitial.

deletion

(dĭ-lē′shən)
n.
1. The act of deleting; removal by striking out.
2. Material, such as a word or passage, that has been removed from a body of written or printed matter.
3. Genetics The loss, as through mutation, of one or more nucleotides from a chromosome.

deletion (del)

[dilē′shən]
Etymology: L, deletionum, destruction
the loss of a piece of a chromosome.

de·le·tion

(dĕ-lē'shŭn)
genetics Any spontaneous elimination of part of the normal genetic complement, whether cytogenetically visible (chromosomal deletion) or inferred from phenotypic evidence (point deletion).
[L. deletio, destruction]

deletion

In genetics, the removal of a segment of DNA with joining up of the cut ends. as in the loss of a segment of a chromosome. Deletion of a single BASE PAIR is one of the kinds of point mutation. Deletion of a base pair triplet (codon) will result in a protein with a missing amino acid.

Deletion

The absence of genetic material that is normally found in a chromosome. Often, the genetic material is missing due to an error in replication of an egg or sperm cell.

deletion

in genetics, loss of genetic material from a chromosome.
References in periodicals archive ?
In addition, the assay allows the identification of somatic deletions in neurofibromas and other NF1 traits that require the double inactivation of the NF1 gene, when the deletion is present in at least 44% of the tissue sample.
Even though our study demonstrated that p16 deletion is an uncommon event in solitary fibrous tumor, there was a trend for p16 deletion to occur more frequently in clinically aggressive tumors.
Phenotypic variation within European carriers of the Y-chromo somal gr/gr deletion is independent of Y-chromosomal background.
The fragment that spanned the deletion junction represented the mtDNA 4977 bp deletion [18].
Deletion Inheritance Mechanism X;autosome translocations X-linked Serine-threonine kinase 9 gene disruption Deletion of the MAGI2 gene Variable Disruption of the on chromosome 7qll.
The fact that [the deletion mutation] is seen extremely rarely in the general population not only establishes a significant difference between rates in autism and control populations, but also unambiguously establishes that strong natural selection is acting against transmission of this deletion (as might be expected from an allele that increases the risk of autism by as much as a factor of 100), given how often it arises de novo in a single generation," added the researchers, whose study was funded by several organizations, including the Autism Consortium.
Duplications in addition to terminal deletions are present in a proportion of ring chromosomes: Clues to the mechanisms of formation.
Xp21 contiguous gene deletion is a microdeletion syndrome with intellectual disability,congenital adrenal hypoplasia,glyserol kinase deficiency and dystrophinopathy.
Alpha (a) thalassemia is a monogenic disease that characterized by decrease or absent synthesis of the a-globin chains due to deletion or mutation in a-globin gene.
THE deletion of a company from the registry of the Registrar of Companies can be effected through liquidation or when it is not carrying out any business or fails to submit to the Registrar the documents required by law or even when the company itself causes its deletion through a relevant letter to the Registrar.