delayed graft


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graft

 [graft]
1. any tissue or organ for implantation or transplantation.
2. to implant or transplant such tissues. This term is preferred over transplant in the case of skin grafts. See also implant.
allogeneic graft allograft.
autodermic graft (autoepidermic graft) a skin graft taken from the patient's own body.
autologous graft (autoplastic graft) a graft taken from another area of the patient's own body; called also autograft.
avascular graft a graft of tissue in which not even transient vascularization is achieved.
bone graft bone transplanted from one site to another.
bypass graft an autograft consisting of a segment of vein or artery grafted into place in a bypass.
cable graft a nerve graft made up of several sections of nerve in the manner of a cable.
coronary artery bypass graft (CABG) see under bypass.
cutis graft dermal graft.
delayed graft a skin graft that is sutured back into its bed and subsequently used after several days.
dermal graft (dermic graft) a skin graft of dermis, used instead of fascia in various plastic procedures.
epidermic graft a skin graft in which a piece of epidermis is implanted on a raw surface.
fascia graft a graft of fibrous tissue, usually taken from the external investing fascia of the lower limb (fascia lata).
fascicular graft a nerve graft in which bundles of nerve fibers are approximated and sutured separately.
filler graft one used for the filling of defects, as the filling of depressions with fatty tissue or of a bony cyst cavity with bone chips or dried cartilage.
free graft a graft of tissue completely freed from its bed, in contrast to a flap.
full-thickness graft a skin graft consisting of the full thickness of the skin, with little or none of the subcutaneous tissue.
heterodermic graft a skin graft taken from a donor of another species.
heterologous graft (heteroplastic graft) xenograft.
homologous graft a graft of tissue obtained from the body of another animal of the same species but with a genotype differing from that of the recipient; called also allograft and homograft.
inlay graft a skin graft or mucosal graft applied by spreading the graft over a stent and suturing the graft and mold into a prepared pocket.
isogeneic graft (isologous graft) (isoplastic graft) syngraft.
lamellar graft replacement of the superficial layers of an opaque cornea by a thin layer of clear cornea from a donor eye.
mesh graft a type of split-thickness graft in which many tiny splits have been made in the skin to allow it to be stretched to cover a larger area.
Mesh skin graft applied to the leg. From McQuillan et al., 2002.
Ollier-Thiersch graft a very thin skin graft in which long, broad strips of skin, consisting of the epidermis, rete, and part of the corium, are used.
omental graft a segment of omentum and its supplying vasculature, transplanted as a free flap to another area and revascularized by anastomosis of arteries and veins.
pedicle graft pedicle flap.
penetrating graft a full-thickness corneal transplant.
periosteal graft a piece of periosteum to cover a denuded bone.
Phemister graft a bone graft of cortical bone with cancellous bone chips to enhance callus formation.
pinch graft a small piece of skin graft, partial or full thickness, obtained by elevating the skin with a needle and slicing it off with a knife.
porcine graft a split-thickness graft of skin from a pig, applied to a denuded area on a human as a temporary dressing for treatment of a severe burn.
sieve graft a skin graft from which tiny circular islands of skin are removed so that a larger denuded area can be covered, the sievelike portion being placed over one area, and the individual islands over surrounding or other denuded areas.
skin graft a piece of skin transplanted to replace a lost portion of skin; see also skin grafting.
split-skin graft (split-thickness graft) a skin graft consisting of the epidermis and a portion of dermis.
Diagram of a cross-section of the skin, demonstrating split thickness and full thickness skin grafts. From Roberts and Hedges, 1991.
syngeneic graft syngraft.
thick-split graft a skin graft consisting of the epidermis and about two thirds of the dermis.
Thiersch graft Ollier-Thiersch graft.

de·layed graft

delaying application of a skin graft for several days until recipient bed is surgically clean or homostasis is adequate.

delayed graft

Etymology: ME, delaein, to leave; Gk, graphein, stylus
a type of skin graft that is partially elevated and reinserted later in the same place.

de·layed graft

(dĕ-lād' graft)
Application of a skin graft after waiting several days for healthy granulations to form.
References in periodicals archive ?
In case delayed graft function occurred, its duration was shorter after machine perfusion compared with cold storage (10 days vs.
Nomogram for predicting the likelihood of delayed graft function in adult cadaveric renal transplant recipients.
In September 2010, Quark initiated a Phase II trial of QPI-1002 for the prophylaxis of delayed graft function (DGF) in patients receiving deceased donor kidney transplants.
NX001 has demonstrated promising activity in preclinical models of acute renal failure, and this clinical program is designed to test its effectiveness in helping to prevent or treat delayed graft function in renal transplant patients, a condition that currently lacks effective treatment options," said James Koziarz, Ph.
The aim of the study is to reduce delayed graft function, which is difficult for the patient, increases costs, and negatively impacts long-term graft survival," said Arie Oosterlee, MD, MBA, director of the Eurotransplant International Foundation.
Its portfolio includes i) products for prevention and treatment of rejection, THYMOGLOBULIN(R) and LYMPHOGLOBULINE(R), polyspecific antibodies currently distributed in Europe and other countries, ii) Odulimomab (anti-LFA-1), a monoclonal antibody currently in Phase III for prevention of delayed graft function in transplant patients, and iii) Celsior(R), an organ preservation solution.
In kidney recipients with a 0% PRA, the cold ischemia time was shorter and the incidence of delayed graft function was lower in subjects without a pretransplant crossmatch.
Quark is currently conducting a Phase II clinical trial of QPI-1002 for the prevention of acute kidney injury in patients undergoing cardiac surgery and for delayed graft function in kidney transplant patients.
Delayed graft function appeared to be affected more by cold ischemia time than by the number of HLA mismatches.
Reporting their findings in the May 1999 issue of the American Journal of Kidney Disease, the authors noted that delayed graft function was more than twice as common in the hemodialysis group compared to those given peritoneal dialysis, with rates of 50.
Food and Drug Administration (FDA) has granted orphan drug designation to its lead product NX001 for the prevention of delayed graft function (DGF) in renal transplant recipients.
IMTIX portfolio includes a) products for prevention and treatment of rejection, Thymoglobulin and Lymphoglobuline, polyspecific antibodies currently distributed in Europe and other countries, b) Odulimomab, a monoclonal antibody currently in Phase III trials in the US and Europe for prevention of delayed graft function in transplant patients, and c) Celsior, an organ preservation solution.

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