delayed extraction


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delayed extraction

An experimental technique in time-of-flight mass spectrometry in which improved mass resolution is obtained by using a controlled delay between the initial pulse of ion formation and acceleration of the ions into the instrument’s flight tube.
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Applications of delayed extraction matrix-assisted laser desorption ionization time-of-flight mass spectrometry to oligonucleotide analysis.
Gridless delayed extraction (15) MALDI-MS analyses were performed with a REFLEX 11 (Broker-Franzen Analytik) instrument operating in positive linear mode, using dihydroxyacetophenone as matrix and following the procedure of Pitt and Gormann (16).
The recent launch of instruments based on Delayed Extraction Technology has dramatically improved time-of-flight mass spectrometry, making it routinely applicable to a wide range of biological applications.

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