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delavirdine

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delavirdine /del·a·vir·dine/ (del″ah-vir´dēn) an antiretroviral, inhibiting reverse transcriptase; used as the mesylate salt in the treatment of HIV infection.
del·a·vir·dine (dl-vîrdn)
n.
A non-nucleoside analog that is used as an antiviral drug in the treatment of HIV infection.

delavirdine,
a nonnucleoside reverse transcriptase inhibitor.
indications It is used to treat HIV-1 in combination with zidovudine or didanosine.
contraindications Known hypersensitivity to this drug or to atevirdine prohibits its use.
adverse effects Life-threatening effects are hepatotoxicity, neutropenia, leukopenia, thrombocytopenia, anemia, granulocytopenia, and nephrotoxicity. Other adverse effects include diarrhea, abdominal pain, nausea, fatigue, headache, rash, pain, myalgia, vomiting, and dyspepsia.

delavirdine [del″ah-vir´dēn]
an antiretroviral agent, that acts as a non-nucleoside reverse transcriptase inhibitor; administered orally as the mesylate salt in treatment of human immunodeficiency virus infection.


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Patients whose background treatment regimen included a protease inhibitor or delavirdine received the lower dose.
1997 * The FDA approves the NNRTI delavirdine (Rescriptor).
AMPRENAVIR AND DELAVIRDINE INTERACTION Researchers in Denmark report that the protease inhibitor amprenavir (Agenerase) lowers the levels of delavirdine (Rescriptor).
 
 
 
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