dehydrocorticosterone

dehydrocorticosterone

(dē-hī″drō-kor-tĭ-kōs′tĕr-ōn)
A physiologically active steroid, C21H28O4, isolated from the adrenal cortex. It is important in water and salt metabolism. Also called 11-dehydrocorticosterone.
References in periodicals archive ?
The isoenzyme, 11 [beta] HSD1, facilitates the regeneration of active cortisol and corticosterone (both 11 hydroxy glucocorticoids) from their inactive forms, cortisone and 11 dehydrocorticosterone by oxidoreductase (11 [beta] reductase) action.
In vitro F and B bind to the MR with affinity equal to that of aldosterone [5], whereas in vivo, 11-HSD-2 transforms F and B (but not aldosterone) into their respective metabolites E and dehydrocorticosterone, which have much less affinity for the MR.