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dehydratase

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dehydratase /de·hy·dra·tase/ (de-hi´drah-tās) a common name for a hydro-lyase.
de·hy·dra·tase (d-hdr-ts, -tz)
n.
An enzyme that catalyzes the removal of oxygen and hydrogen from organic compounds in the form of water.

dehydratase
any enzyme of the lyase class that catalyzes the removal of H2O, leaving double bonds (or adding groups to double bonds).


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Moreover, this explanation is supported by recent findings in lead-exposed workers showing in addition that the renal response to lead, including hyperfiltration, was modulated by genetic polymorphisms in [delta]-aminolevulinic acid dehydratase (ALAD 2 allele or ALAD 1-2 genotype) and nitric oxide synthase (eNOS variant allele) genes (Weaver et al.
Lead directly inhibits the activity of the cytoplasmic enzyme [delta]-aminolevulinic acid dehydratase (ALAD), resulting in a negative exponential relationship between ALAD and BPb.
We analyzed data on three such genetic polymorphisms: [delta-aminolevulinic acid dehydratase (ALAD), endothelial nitric oxide synthase (eNOS), and the vitamin D receptor (VDR).
 
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