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dehydratase |
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dehydratase /de·hy·dra·tase/ (de-hi´drah-tās) a common name for a hydro-lyase.
dehydratase any enzyme of the lyase class that catalyzes the removal of H2O, leaving double bonds (or adding groups to double bonds). How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Moreover, this explanation is supported by recent findings in lead-exposed workers showing in addition that the renal response to lead, including hyperfiltration, was modulated by genetic polymorphisms in [delta]-aminolevulinic acid dehydratase (ALAD 2 allele or ALAD 1-2 genotype) and nitric oxide synthase (eNOS variant allele) genes (Weaver et al. Lead directly inhibits the activity of the cytoplasmic enzyme [delta]-aminolevulinic acid dehydratase (ALAD), resulting in a negative exponential relationship between ALAD and BPb. We analyzed data on three such genetic polymorphisms: [delta-aminolevulinic acid dehydratase (ALAD), endothelial nitric oxide synthase (eNOS), and the vitamin D receptor (VDR). |
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