degranulation

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de·gran·u·la·tion

(dē-gran'yū-lā'shŭn),
Disappearance or loss of cytoplasmic granules from a cell or activation of granulocytic cells (for example, neutrophils, mast cells, basophils, eosinophils).

degranulation

(dē-grăn′yə-lā′shən)
n.
The process of losing granules.

degranulation

[dēgran′yəlā′shən]
the release of granules from cells, such as mast cells and basophils.

degranulation

the loss of granules; usually refers to the secretory granules in certain cells, e.g. pituitary chromophobes, acidophils and basophils. In basophils and mast cells, it is associated with the release of active substances from the cells and is characteristic of type I immediate hypersensitivity.
References in periodicals archive ?
Differential regulation of IL-4 expression and degranulation by anti-allergic olopatadine in rat basophilic leukemia (RBL-2H3) cells.
The role of thunberginol A, an isocoumarin constituent of Hydrangeae Dulcis Folium, on the signal transmission pathway for rat mast cell degranulation.
Structural requirements of flavonoids for inhibition of antigen-induced degranulation, TNF-[alpha] and IL-4 production from RBL-2H3 cells.