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degranulation

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degranulation
[dēgran′yəlā′shən]
the release of granules from cells, such as mast cells and basophils.
degranulation
the loss of granules; usually refers to the secretory granules in certain cells, e.g. pituitary chromophobes, acidophils and basophils. In basophils and mast cells, it is associated with the release of active substances from the cells and is characteristic of type I immediate hypersensitivity.
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Quercetin reduces basophil degranulation, (109), (110) and histamine release, (111-113) and dampens the inflammatory response directly by modulating certain key enzymes including lipoxygenase, phospholipases, and nucleotide diesterases.
Immune defense and repair systems in biologic medicine: clinical ... by Jaffe, Russell / Townsend Letter
Immunomodulators Omalizumab is a monoclonal antibody that binds to immunoglobulin E (IgE), thereby neutralizing IgE-mediated responses, which occur from the degranulation of basophils and mast cells.
Asthma medications by Wojciechowski, Bill / FOCUS: Journal for Respiratory Care & Sleep Medicine
Subjects include insights into the role of mast cells in cardiac disease, functional roles of mast cells in the pathyphysiology of cardiovascular disease, mast cells in endometriosis, and mast cell degranulation as an undesirable effect in the development of new drugs.
Mast cells; roles, interactions & disorders by SciTech Book News
 
 
 
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