1) Toxicity, evidenced by increased cytoplasmic basophilia and degranulation
, was also noted among heterophils and, with the presence of a left shift in this series, indicated an inflammatory leukogram.
They are advised to avoid foods, medications, and environmental triggers that can cause mast cell degranulation
The edema component is generated by mast-cell degranulation
and can be uncoupled using selective [H.
Schaafsma and his colleagues suggested that insulin enhances the degranulation
of mast cells so increased release of mediators like histamine and prostaglandins are responsible for airway hyper-reactivity6.
This is a result of the offending agent binding directly to mast cells and inducing their degranulation
with release of inflammatory mediators, particularly histamine,  leading to angio-oedema and urticaria.
8, in methanol),Silanized glass vials containing heparin(N) (porcine), 20 units, for collection of 1-ml whole blood,Siliconized vials for incubation of samples,Stimulant for NBT Assay (Bacterial extracts (nonviable), lyophilized),Nitroblue Tetrazolium (NBT) Reduction Kit,Basophil Degranulation
Eotaxin induces degranulation
and chemotaxis of eosinophils through the activation of ERK2 and p38 mitogen- activated protein kinases.
IN VITRO EFFECT OF THE PROTEIN EXTRACT OF Sarcocystis aucheniae MACROCYSTS ON THE VIABILITY AND DEGRANULATION
OF RABBIT (Oryctologus cuniculus) LEUKOCYTES
It is a chemoattractant that has been found to be elevated in volume during an asthmatic bronchospasm and may have a significant role in triggering the activation and degranulation
of eosinophils [5, 6].
Salmeterol, formoterol, and arformoterol inhibit human mast cell activation and degranulation
in vitro, prevent an increase in vascular permeability with inflammatory mediators, and generally diminish the attraction and accumulation of airway inflammatory cells.
Benzylisoquinolinium compounds, such as d-tubocurarine, metocurine, doxacurium, atracurium, and mivacurium, are more likely to cause direct mast cell degranulation
than aminosteroid compounds such as pancuronium, vecuronium, rocuronium, and pipecuronium.
The type-1 hypersensitivity that causes progressive mast cell degranulation
could be the trigger factor for acute appendicitis.