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deformylase

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deformylase
a prokaryotic enzyme that removes the formyl group from amino acids, e.g. the methionine coded by the initiation codon AUG.
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With detailed methods and protocols, contributors address computational strategies, a number of assay methods (for DNA gyrase, topoisomerase IV, bacterial RNA polymerase, bacterial ribosome biogenesis and inhibitors targeting specific translational steps), high-throughput peptide deformylase inhibitor screening, penicillin-binding protein assay methods, methods for assessing the structure and function of cationic antimicrobial peptides, and bacterial efflux pump inhibitors.
New antibiotic targets by SciTech Book News
In research, British Biotech has two ongoing programs and access to a third a follows: -- an Antibiotic Program based on peptide deformylase inhibitors (PDFIs).
FDA CLEARS THROMBOLYTIC DRUG FOR PHASE II CLINICAL TRIAL by Worldwide Biotech
The lead compounds in British Biotech's in-house antibiotic programme are peptide deformylase inhibitors in development for respiratory tract and other gram positive infections.
British Biotech and MethylGene sign agreement on phase II antisense ... by BIOTECH Patent News
 
 
 
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