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dedifferentiation

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dedifferentiation /de·dif·fer·en·ti·a·tion/ (de-dif″er-en″she-a´shun) anaplasia.
de·dif·fer·en·ti·a·tion (ddf--rnsh-shn)
n.
Regression of a specialized cell or tissue to a simpler unspecialized form.

dedif·fer·enti·ate v.

dedifferentiation.
See anaplasia.

anaplasia [an″ah-pla´zhah]
loss of differentiation of cells and their orientation to each other, a characteristic of tumor cells; called also dedifferentiation and undifferentiation.

dedifferentiation
regression from a more specialized or complex form to a simpler state.


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Since dedifferentiation is an interesting phenomenon probably occurring in a lot of different stem cell populations, we wanted to know more about the process.
Sarcomatoid change represents a high-grade transformation or dedifferentiation in any of the classical variants of renal cell carcinoma (RCC), including chromophobe RCC, and is not a distinct histologic entity.
Against the background of views on social dedifferentiation and the end of the book I emphasise the career value of the humanities.
 
 
 
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