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dedifferentiation
(redirected from dedifferentiate)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.02 sec.
dedifferentiation /de·dif·fer·en·ti·a·tion/ (de-dif″er-en″she-a´shun) anaplasia.
de·dif·fer·en·ti·a·tion (ddf--rnsh-shn)
n.
Regression of a specialized cell or tissue to a simpler unspecialized form.

dedif·fer·enti·ate v.

dedifferentiation.
See anaplasia.

dedifferentiation
regression from a more specialized or complex form to a simpler state.


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As in nonmalignant tumors, cells have lost their normal control, often dedifferentiate, and grow in an inappropriate place.
Reprogramming an adult cell to dedifferentiate it back into pluripotent stem cells is a key proposal (Option 4) in the 2005 President's Council on Bioethics white paper "Alternative Sources of Human Pluripotent Stem Cells.
The most significant seems to be that the worms do not dedifferentiate cells to create the blastema.
 
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