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dedifferentiation |
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dedifferentiation /de·dif·fer·en·ti·a·tion/ (de-dif″er-en″she-a´shun) anaplasia.
dedifferentiation. See anaplasia. dedifferentiation regression from a more specialized or complex form to a simpler state. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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As in nonmalignant tumors, cells have lost their normal control, often dedifferentiate, and grow in an inappropriate place. Reprogramming an adult cell to dedifferentiate it back into pluripotent stem cells is a key proposal (Option 4) in the 2005 President's Council on Bioethics white paper "Alternative Sources of Human Pluripotent Stem Cells. The most significant seems to be that the worms do not dedifferentiate cells to create the blastema. |
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