CLEC6A

(redirected from dectin-2)

CLEC6A

A gene on chromosome 12p13 that encodes a C-type lectin domain protein involved in Ca2+-dependent binding of high-mannose carbohydrates present on the surface of Candida albicans, dust mites and Schistosoma mansoni eggs, altering the adaptive immune response.
References in periodicals archive ?
The major PRRs involved in fungal immune responses are C-type lectin receptors Dectin-1, DC-SIGN, Dectin-2, Mincle, Galectin-3 and Mannose Receptor.
Important exam-ples include MBL, SP-A and SP-D, class A scavenger receptors such as MARCO (macrophage receptor with a collagenous structure), and dectin-1 and dectin-2.
This led us to believe that the dectin-2 promoter might direct expression of other genes to Langerhan's cells," Dr.