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decorin

   Also found in: Wikipedia 0.04 sec.
decorin
a small chondroitin sulfate proteoglycan found in bone, thought to be involved in the organization and mineralization of bone.

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The core proteins bind at specific sites on the surface of fibrils, and the GAG chain extends to form an antiparallel array with a neighboring decorin GAG chain extending from an adjacent fibril.
paid US$500,000 to obtain certain rights to Telios' anti-TGF-Beta antibodies for fibrotic diseases and obtained right of first refusal for Telios' rights to decorin, a mediator of TGF-Beta which plays an important role in dermal scarring and fibrotic diseases.
 
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