decision rule

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Related to decision rule: Bayes decision rule

decision rule

A clinical trial term of art for a succinct statement of how a decision  regarding approval of a new drug application will be reached, based upon the expected foreseen clinical benefits in terms of outcomes of the primary endpoint.


(rool) [Fr. riule fr L. regula, ruler, pattern]
A guide or principle based on experience or observation.

ABCD prediction rule

ABCD score.

ABCD rule

ABCD score.

buccal object rule

A dental radiographical technique used to identify the position of an object within a three-dimensional area. A reference radiograph is taken. The projection angle is changed and the resulting radiograph compared with the reference radiograph. If the image remains in the same position, the object is located buccal to the reference object. If the image changes position, the object is lingual to the reference object.

CHIP rule

A diagnostic prediction rule used to determine if a patient with a minor head injury would benefit from emergent CT imaging of the brain. Low-risk patients are those who have a Glascow Coma Scale (GCS) of 15, and no history of loss of consciousness, amnesia, vomiting, or generalized headache. These patients do not need neuroimaging in the Emergency Department, and can be discharged home with follow-up. Patients who are over 60 years old, or who have a history of alcohol or drug use, epilepsy, or coagulopathy are considered high risk regardless of their GCS. Patients with intermediate findings are considered to have medium-risk mild head injuries.

Cieszynski rule

See: Cieszynski rule

Clark rule

See: Clark rule

Common Rule

Any of the U.S. policies designed to protect the rights and interests of citizens who choose to participate in government-funded biomedical research. Those who choose to participate in biomedical research often suffer from life-altering or life-threatening illnesses. As a result they may be more psychologically vulnerable than others and may agree to become investigative subjects because of fear or desperation. The protections provided by the Common Rule are designed to ensure that agencies that perform federally funded human research respect the rights of experimental subjects. Included are the rights of confidentiality and full disclosure (informed consent). Research performed on children or prisoners is given special protections.

convex-concave rule

, concave-convex rule.
A law of joint kinematics that states that if a convex joint surface moves on a stationary concave surface, the convex joint will slide in the direction opposite that of the angular motion of the bone, and that if a concave joint surface moves on a stationary convex surface, the articular surface will slide in the same direction as the angular motion of the bone.

Cowling rule

See: Cowling rule

decision rule

See: decision aid

Durham rule (of criminal responsibility)

A legal decision from Durham v. United States that limits the culpability of those with psychological or neurological diseases who have committed criminal acts. It states that an unlawful act is not a criminal act if it was committed by someone mentally ill, e.g., psychotic at the time, or was committed by someone with profound neurological disease, e.g., with severe dementia or organic brain injury.

learned intermediary rule

Learned intermediary doctrine.

mature minor rule

Any of the regulations in some states that allow the practitioner to treat minors without parental consent if the minor is deemed to be capable of understanding the nature and consequences of the treatment and if the treatment is of benefit to the minor.

modified Ottawa ankle rules

See: modified Ottawa ankle rules
Enlarge picture

rule of nines

A formula for estimating percentage of body surface areas, particularly helpful in judging the portion of skin that has been burned. For the adult, the head represents 9%; each upper extremity 9%; the back of the trunk 18%, and the front 18%; each lower extremity 18%; and the perineum the remaining 1%.
See: illustration

Ottawa ankle rules

See: Ottawa ankle rules

rule of ten

The criteria used to judge the readiness of an infant for surgical repair of a cleft lip. The infant must weigh 10 lb, be 10 weeks old, have a hemoglobin value of 10 g, and have a white blood cell count less than 10,000.

rule of thirds

The classification of bone shaft fractures: proximal third, midshaft, and distal third. Midshaft fractures heal more slowly than other fractures because the blood supply in the middle of a bone is less than that at either end.

van't Hoff rule

See: van't Hoff, Jacobus Henricus
References in periodicals archive ?
As we showed in our original paper, however, the higher the incidence, the more cost-effective either the clinical decision rule or 'Treat All' strategies become, which makes our results even more applicable to regions with higher incidence.
Decision rules, such as the ones in Figure 3, have to be defined for all aggregate attributes in the model.
Practically, it consists in inferring a set of decision rules from some holistic information in terms of assignment examples provided by the decision makers.
An ABM simulation's test of fit is riot "variance explained" but, rather, a generated observable pattern using the fewest number of plausible decision rules and agents (Gilbert, 2008).
Performance of a decision rule to predict need for computed tomography among children with blunt head trauma.
In addition to the disorder-based decision rule, the growth-rate is also a necessary condition for enhancing the reliability of smoke validation.
Conclusion: Some clinical decision rules for radiological imaging exist but physiotherapists do not universally accept them.
Patients with a "likely" PE based on the decision rule and those who were "unlikely" based on the decision rule but who had an elevated D-dimer underwent CT.
After some exploratory analyses of the simple clusters in Simu 1 and Simu 2, we found that a suitable decision rule for the MIX model in these two scenarios is to choose [R.
When a single decision rule is estimated, we reject the null hypothesis at the 10 percent level (chi-square = 7.