decerebrate


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decerebrate

 [de-ser´ĕ-brāt]
1. to eliminate cerebral function by transection of the brainstem or ligation of the common carotid arteries and basilar artery at the center of the pons.
2. a laboratory animal so prepared.
decerebrate rigidity a posture found in those with lesions of the upper part of the brainstem or severe bilateral lesions of the cerebrum; the patient lies in rigid extension with the arms internally rotated at the shoulders, elbows, knees, and hips extended, and fingers, ankles, and toes flexed. The jaw may be clenched with the neck hyperextended. Called also decerebrate posturing.
Decerebrate rigidity (or posturing).

de·cer·e·brate

(dē-ser'ĕ-brāt),
1. To cause decerebration.
2. Denoting an animal so prepared, or a patient whose brain has suffered an injury that renders the patient, in neurologic behavior, comparable with a decerebrate animal.

decerebrate

/de·cer·e·brate/ (-ser´ĕ-brāt) to eliminate cerebral function by transecting the brain stem or by ligating the common carotid arteries and basilar artery at the center of the pons; an animal so prepared, or a brain-damaged person with similar neurologic signs.

decerebrate

(dē-sĕr′ə-brāt′)
tr.v. decere·brated, decere·brating, decere·brates
To eliminate cerebral brain function in (an animal) by removing the cerebrum, cutting across the brainstem, or severing certain arteries in the brainstem, as for purposes of experimentation.
adj. (also -brĭt)
1. Deprived of cerebral function, as by having the cerebrum removed.
2. Resulting from or as if from decerebration: decerebrate rigidity; decerebrate movements.
3. Lacking intelligence or reason.
n. (also -brĭt)
A decerebrate animal or person.

de·cer′e·bra′tion n.

decerebrate

[dēser′əbrāt]
1 lacking a cerebrum.
2 lacking neural communication between the cerebrum and lower portions of the central nervous system.

de·cer·e·brate

(dē-ser'ĕ-brāt)
1. To cause decerebration.
2. Denoting an animal so prepared, or a patient whose brain has suffered an injury causing neurologic impairment comparable with that of a decerebrate animal.

decerebrate

Suffering from the effects of loss of cerebral activity, such as thought, consciousness, sensation and the power of voluntary movement.

decerebrate

to eliminate cerebral function by transecting the brainstem or by ligating the common carotid arteries and basilar artery at the center of the pons; an animal so prepared, or a brain-damaged animal with similar neurological signs.

decerebrate rigidity
rigid extension of the limbs as a result of decerebration; also occurs as a result of lesions in the upper brainstem.
References in periodicals archive ?
Motor-unit activation patterns in lengthening and isometric contractions of hindlimb extensor muscles in the decerebrate cat.
John had the symptoms of a person who was about to die: his pupils would not constrict to light and his posture on the stretcher was decerebrate.
During the course of treatment she developed high grade fever, myoclonic jerks, irregularity of respiration, decerebrate posturing, fluctuation of BP, and died after 64 h of admission.
Glasgow Coma Scale Eye-opening Opens eves spontaneously 4 points response Opens eyes in response to voice 3 points Opens eyes in response 2 points to painful stimuli Does not open eyes 1 point Verbal orientated, converses normally 5 points response Confused, disorientated 4 points conversation, but able to answer basic questions Inappropriate responses, 3 points words discernible Incomprehensible speech 2 points Makes no sounds I point Motor Obeys commands for movement 6 points response Purposeful movement 5 points to painful stimulus Withdraws from pain 4 points Abnormal (spastic) flexor 3 points response to painful stimuli, decorticate posture Extensor response to painful 2 points stimuli, decerebrate posture Makes no movements 1 point Table III.
The third and fourth stages include increasing obtundation, amnesia, nystagmus, clonus, and muscular rigidity and may progress to coma, decerebrate posturing, dilated pupils, and poor response to painful stimuli.
On arrival at the emergency department, the patient was decerebrate to noxious stimuli, and his pupils were unequal and sluggish.
A I ALWAYS find it depressing when I discover yet another entirely decerebrate individual among my readers.
These behavioral similarities between decerebrate and normal newborns are consistent with current knowledge of developmental neuroanatomy: even though cerebral hemispheres are present in gross structure in normal newborns, they are very immature microscopically compared to the brainstem.
Proprioceptive modulation of hip flexor activity during the swing phase of locomotion in decerebrate cats.
Carbachol injections into these sites induced atonia in decerebrate cats (88) and REM sleep in freely moving rats (89,90).
III, IV), from moderate to severe headache, nuchal rigidity 3 Mild focal deficit, lethargy, or confusion 4 Stupor, from moderate to severe hemiparesis, early decerebrate rigidity 5 Deep coma, decerebrate rigidity, moribund appearance Note: From "Surgical Risk related to time of intervention in the repair of intracranial aneurysms," by W E Hunt and R.
He required complete ventilator support, his pupils remained dilated and fixed, and his only response to stimuli was decorticate or decerebrate posturing.