deaminases

de·am·i·nas·es

(dē-am'i-nā-sĕz),
Enzymes catalyzing simple hydrolysis of C-NH2 bonds of purines, pyrimidines, and pterins, thus producing ammonia (usually named in terms of the substrate, for example, guanine deaminases, adenosine deaminases, AMP deaminases, pterin deaminases); not generally used for deamination of noncyclic amides. Deaminases are distinguished from ammonia-lyases in that the latter produce an unsaturation at the point of NH3 removal.
Synonym(s): deaminating enzymes

de·am·i·nas·es

(dē-am'i-nā-sĕz)
[EC group 3.5.4] Enzymes catalyzing simple hydrolysis of C-NH2 bonds of purines, pyrimidines, and pterins.
Synonym(s): deaminating enzymes.
References in periodicals archive ?
The proteins, known as APOBEC cytidine deaminases, cause clusters of mutations that can outnumber all others associated with cancer, say the researchers.
corresponding author of the paper, said that scientists knew the main functions of APOBEC cytosine deaminases were to inactivate viruses that attack the body and prevent ancient viruses present in the human genome from moving around and causing disrupting mutations.
Non-Giusti methods includes the reduced nicotinamide adenine dinucleotide-linked kinetic method, ADA deaminases adenosine to inosine.
The analysis of pleural fluid adenosine deaminase (ADA) levels in the diagnosis of tuberculous pleural effusion (TPE) was established in 1978 by Piras et al (1).
Adenosine deaminase (ADA) is an enzyme in the purine salvage pathway that catalyses the conversion of adenosine and deoxyadenosine to inosine and deoxyinosine with the release of ammonia.
There are no international standardisation programs for adenosine deaminase assays and published cut-off should therefore be viewed with caution.
However, if clinical details suggest a high pre-test probability, adenosine deaminase results should be interpreted with caution.
Adenosine deaminase activity in pleural effusions: an aid to differential diagnosis.
Diagnostic value of adenosine deaminase in tuberculous pleural effusions: a meta-analysis.
A reduced nicotinamide adenine dinucleotide-linked kinetic assay for adenosine deaminase activity.
The enzymes responsible for A to I editing, the adenosine deaminases acting on RNA (ADARs), specifically recognize partially double-stranded (ds) RNA structures where they modify individual adenosines to inosine depending on the local structure and sequence environment.