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deaminase |
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deaminase /de·am·i·nase/ (de-am´ĭ-nās) an enzyme causing deamination, or removal of the amino group from organic compounds, usually cyclic amidines.
deaminase [dē·am′inās] Etymology: L, de, away, amine, ammonia; Fr, diastase, enzyme one of the subclasses of enzymes that catalyze the hydrolysis of the NH2 bond in amino compounds. The enzymes are usually named according to the substrate, such as adenosine deaminase, guanine deaminase, or guanosine deaminase. Also called aminohydrolase. deaminase [de-am´ĭ-nās] an enzyme causing deamination (removal of the amine group from a compound); enzymes are named according to substrate, such as adenosine deaminase, cytidine deaminase, guanine deaminase, etc.
deaminase an enzyme causing deamination, or removal of an amino group from organic compounds, named according to its substrate as adenosine deaminase, cytidine deaminase, guanine deaminase, etc. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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acute intermittent porphyria ADA ADD adenosine adenosine deaminase adenosine deaminase deficiency adenosine triphosphatase aminohydrolase arginine arginine vasopressin Bubble Boy Bubble Boy Disease cartilage-hair hypoplasia syndrome gene therapy guanase guanine deaminase guanosine deaminase immunodeficiency intermittent acute porphyria | A research team from United States and China suggests adenosine deaminase enzyme therapy could successfully prevent or treat penile fibrosis in men with priapism. All 10 children who had SCID caused by a lack of adenosine deaminase were still alive a median of four years after the missing enzyme was replaced, Maria-Grazia-Roncarolo, MD, of the San Raffaele Telethon Institute for Gene Therapy in Milan, Italy, and colleagues reported in the January 29 issue of the New England Journal of Medicine (NEJM). They address the move toward a universal platform for autologous stem cell gene therapy and also address adenosine deaminase deficiency, insertion of a transgene into Chromosome 19, site-specific integrating vectors, gene targeting, engineering of homing endonucleases and novel sequence-specific DNA binding and modifying, gene targeting mediated by hyper-dependent adenoviral vectors, and multipotent progenitor cells. |
deaminase |
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