de Lange syndrome

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de Lang·e syn·drome

a multiple congenital anomaly syndrome characterized by mental retardation, distinctive facies with microcephaly, synophrys, low anterior hairline, depressed nasal bridge, anteverted nares, long philtrum, carp mouth, thin upper lip and low-set ears, prenatal and postnatal growth retardation, hirsutism, and frequently, limb anomalies. Genetics unclear, although some instances appear to be autosomal dominantly inherited.

de Lange syndrome

(də lăng′, də läng′, dĕ läng′ə)

de Lange syndrome

(de lang')
[Cornelia de Lange, Dutch pediatrician, 1871–1950]
See: Cornelia de Lange syndrome

de Lange,

Cornelia, Dutch pediatrician, 1871-1950.
Cornelia de Lange syndrome - Synonym(s): de Lange syndrome
de Lange syndrome - a congenital anomaly characterized by impaired development, mental retardation, characteristic facies with synophrys and hairline well down on forehead, depressed bridge of nose with uptilted tip of nose, small head with low-set ears, and flat spadelike hands with simian crease and short tapering fingers. Synonym(s): Amsterdam syndrome; Cornelia de Lange syndrome
References in periodicals archive ?
Simon, who had rare genetic disorder Cornelia de Lange Syndrome and was only the size of a seven year old, was sent home after the tube had been fitted.
The inquiry at Glasgow Sheriff Court had been told Simon, of Knightswood, Glasgow, had been born with a rare genetic condition, Cornelia de Lange syndrome.
Devon suffers from Cornelia de Lange Syndrome, a rare genetic condition that affects about one in 40,000 babies born each year.
Corneelia de Lange Syndrome (CDLS) is a genetic disorder present from birth not normally associated with any family history.
Central Lakes Search and Rescue, Carlos, MN -- Chattanooga CARES HIV/AIDS Resource Center, Chattanooga, TN -- College Corner Older Adult Ministries, West College Corner, IN -- Commission On Missing & Exploited Children, Memphis, TN -- Comprenew Academy, Grand Rapids, MI -- Cornelia de Lange Syndrome Canada, Fort Erie, Ontario -- Council for Advancement and Support of Education, Washington D.
I was pleased to read that June Jones probably would not have chosen to abort her daughter Natasha, who has Cornelia de Lange syndrome (Chronicle, April 20).
Devon has Cornelia de Lange Syndrome, a rare genetic condition which affects growth, mental development, speech, hearing, digestion and behaviour.
The teenager had the rare Cornelia de Lange Syndrome, needed 24-hour care and was unable to walk or sit up without assistance.
PHILADELPHIA, May 17 /PRNewswire/ -- An international team of researchers has discovered the gene for Cornelia de Lange syndrome, a disabling, multisystem genetic disease that affects an estimated one in 10,000 children.
George Wimpey made the donation to Devon Barnes, who suffers from cornelia de lange syndrome which affects approximately one in every 50,000 babies born.
George Wimpey North has donated pounds 1,000 to Devon Barnes, aged seven, who suffers from Cornelia de Lange Syndrome.